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The Geophysical Light/Dark Cycle
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This is an activity (located on page 131 of the PDF) related to sleep and circadian rhythms as well as space travel.

Cooling Off
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In this activity, learners are introduced to challenges of maintaining temperatures while living in space.

Building a Magic Carpet
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In this activity (page 89 of the PDF), learners compare and contrast pitch and roll motions by using a Magic Carpet maze similar to one that was used for Neurolab investigations about microgravity.

Building a 3-D Space Maze: Escher Staircase
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In this activity (page 95 of the PDF), learners create Escher Staircase models similar to those that were used by Neurolab's Spatial Orientation Team to investigate the processing of information about
Butterflies in Space
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The Butterflies in Space Teacher's Guide uses "life in space" to encourage learners to conduct their own open-ended scientific investigations.
Bag of Bones
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In this activity, learners will use cereal to conduct an experiment and investigate how decreased bone density is related to increased risk of bone fracture.