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Multifactorial Inheritance
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In this biology activity (page 6 of the PDF), learners roll a die to create a simple model that teaches them about the factors contributing to heart disease.

Wear a Chimp on Your Wrist
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Learners construct a bracelet containing two strands of beads, which represents a double strand of DNA that codes for a gene. They match beads to the bases in a section of a chimp's DNA code.