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This is an activity (located on page 131 of the PDF) related to sleep and circadian rhythms as well as space travel.

In this activity about humans and space travel (page 1 of PDF), learners compare and contrast the behavior of a water-filled plastic bag, both outside and inside of a container of water.

In this activity about the circulatory system and space travel (on page 38 of the PDF), learners use water balloons to simulate the effects of gravity and microgravity on fluid distribution in the bod

The Butterflies in Space Teacher's Guide uses "life in space" to encourage learners to conduct their own open-ended scientific investigations.