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How Do Viruses Recognize a Target Cell?
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This activity demonstrates the specificity of viral vectors for target cells in gene therapy delivery methods using two approaches: 1) STYROFOAM® models demonstrate viral ligand binding to receptor pr
Drain Game
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In this activity (on pages 36-39), learners make a model of a watershed out of paper, then run water down the mountain to simulate how rainfall and pollution affect watersheds.
Space Stations: Sponge Spool Spine
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In this activity, learners simulate what happens to a human spine in space by making Sponge Spool Spines (alternating sponge pieces and spools threaded on a pipe cleaner).
Bend It, Break It
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In this activity (on pages 25-32 of PDF), learners make models of the inner ear out of pipe cleaners.
You Can't Take It With You
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This activity models the necessary balance of creating power and cleaning up its associated waste. Learners participate in a game where they attempt to move forward toward a goal.
Human-powered Orrery
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In this space science activity, learners work together to create a human-powered orrery to model the movements of the four inner planets.
Infant Moon: Moon Mix!
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In this activity, learners investigate the Moon's infancy and model how an ocean of molten rock (magma) helped shape the Moon that we see today.
Rippin' Rockets
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In this activity, learners work in pairs to conduct a series of experiments using a balloon, drinking straw, and paper.
Glass and Mirrors: An Inside Look at Telescopes
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This hands-on astronomy activity allows you to create a “cutaway” telescope to clearly show how reflector and refractor telescopes work.
Cook Up a Comet
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In this activity (on page 5 of PDF), learners use dry ice and household materials to make scientifically accurate models of comets.
Gas Model
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This highly visual model demonstrates the atomic theory of matter which states that a gas is made up of tiny particles of atoms that are in constant motion, smashing into each other.
Inner Space
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In this activity, learners discover that there is space between molecules even in a cup "full" of water. They first fill a cup with marbles, and then add sand to fill the gaps between the marbles.
Freezing Lakes
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In some parts of the world, lakes freeze during winter. In this activity learners will explore water’s unique properties of freezing and melting, and how these relate to density and temperature.
Mars from Above: Carving Channels
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In this activity, learners create channel features with flowing water, comparing their observations to real images of Mars and Earth taken by satellites/orbiters.
Low-Tech Water Filter for High-Impact Clean
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In this activity, learners consider the water features they might enjoy at a community park--a pond, brook, water playground (or "sprayground"), or pool--and what happens to the water over time.
Teen Moon: Moon Ooze
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In this activity, learners model how the Moon's volcanic period reshaped its earlier features.
Levers at Play
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In this activity, learners consider how a simple machine, a lever, turns a small push or pull (a small force) into a larger--or stronger--push or pull (a larger force).
Jump to Jupiter
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In this activity, learners help create and then navigate an outdoor course of the traditional "planets" (including dwarf planet Pluto), which are represented by small common objects.
Balloon Impacts
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In this activity, learners measure the diameter of their water balloons, model an impact, measure the diameter of the “crater” area, and determine the ratio of impactor to crater.
Balloon Bugs
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In this activity, learners make balloon models of disease-causing bacteria.