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In this activity, learners examine antibodies and antibody recognition using a model. Learners will process a sensor array to determine the disease a patient may have based on the biosignature defined on the array. Learners discover just how many millions of signals their bodies give off every day, and how scientists use those signals to build a "lab-on-a-chip"--technology that could be used in the near future to diagnose and detect illnesses in patients before symptoms appear on a macro level. [Activity is publicly available through a web crawler capture on Archive.org.]
- 10 to 30 minutes
- 45 to 60 minutes
- Over $20 per group of students
- Ages 11 - 14
- Activity, Lesson/Lesson Plan, Simulation
- English
Quick Guide
Materials List (per group of students)
- Safety glasses
- Non-latex gloves
- Glossary Master (for Educator)
- Valley Fever Arrays Poster
- Microbe/Antibody/Array Model(s)
- 10 Array Simulation Kits
- Sensor Array Protocol
- Transfer Pipettes
- 1.5mL Tube of Saliva (1mL of water)
- Dropper Bottle with Detection Solution (25 mL of 1M NaOH)
- Dropper Bottle with Wash Buffer (30 mL of distilled water)
- Ziploc entree container with Lid
- 1 Sensor Array
- 1 laminated Diagnosis Key
- 1 paper towel sheet, folded to fit the bottom of each Ziploc container
- 10 Timers
- Reflection Questions
- Tube labels (Avery 8195 2/3” x 1 ¾”)
Subjects
-
Engineering and Technology
-
Engineering
- Bioengineering/Biomedical Engineering
- Nanotechnology
-
Technology
- Medical Technology
-
Engineering
-
Life Sciences
-
Cells
- Cell Structure and Function
-
Heredity and Genetics
- DNA Structure and Function
-
Human Body
- Medicine
- Immune System
-
Cells
-
Physical Sciences
- Chemistry
-
The Nature of Science
-
The Scientific Process
- Conducting Investigations
- Gathering Data
- Formulating Explanations
- Communicating Results
- Science as a Career
-
The Scientific Process
-
The Nature of Technology
-
Technology and Society
- Impacts of Technology
-
Technology and Society
Audience
To use this activity, learners need to:
- see
- read
- touch
Learning styles supported:
- Involves teamwork and communication skills
- Involves hands-on or lab activities
Other
Includes alignment to state and/or national standards:
Access Rights:
- Free access
By:
Rights:
- All rights reserved, Arizona Science Center, 2012
Funding Source:
- Science Education Partnership Award, National Institutes of Health