In this chemistry challenge, learners discover that many chemical reactions involve heat loss or gain. With this understanding, they try to find a combination of chemicals that could be used to make an instant cold pack. They are given baking soda, ammonium nitrate, calcium chloride, and potassium chloride, along with vinegar and water (3% hydrogen peroxide and yeast can also be used). Learners combine chemicals into calorimeters, then use thermometers to measure how the temperature changes. Calorimeters can be made by pushing a heated test tube into home insulation foam (instructions in PDF) or can be purchased (one source is Flinn Scientific). The water and ammonium nitrate, and vinegar and baking soda, are candidates for making a cold pack.