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The Game of Life: Stem Cell Edition
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In this activity, learners play a game that models what happens as stem cells differentiate into different cell types.

Body Biographies
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In this activity, learners will learn about a person they admire (famous, family or otherwise) or even themselves and create a life-sized silhouette.

Virtual Farm Management
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This activity (located on page 3 of the PDF under GPS: Farm Animals Activity) is a full inquiry investigation into raising livestock.

Locating a Point
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In this activity, learners work in teams to simulate the process used by Global Positioning Systems (GPS) to determine the location of a fallen meteorite in Antarctica.

Malformed Frogs
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This activity (on page 2 of the PDF under SciGirls Activity: Malformed Frogs) is a full inquiry investigation into using indicator species to assess the health of an environment.

Draw a Monarch Butterfly: Scientific Illustration
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Ivy Rutzky, a scientific assistant at the American Museum of Natural History, introduces an activity where learners create a scientific illustration of a monarch butterfly.
Butterflies in Space
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The Butterflies in Space Teacher's Guide uses "life in space" to encourage learners to conduct their own open-ended scientific investigations.