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Learners observe a model of a cell and its chromosomal DNA made from a plastic egg and dental floss. Use this model to illustrate how much DNA is held in one cell.

In this team design challenge (page 19-24 of PDF), learners "land" a model Lunar Rover in a model Landing Pod (both previously built in activities #3 and #4 in PDF).

In this activity on page 3 of the PDF, learners visualize the relative size and structural differences between microbes that have the potential to cause disease.

In this activity, learners simulate nature's water filtration system by devising a system that will filter out both visible and invisible pollutants from water.

In this team design challenge (page 2-10 of PDF), learners design and build a model of a Lunar Transport Rover that will carry equipment and people on the surface of the Moon.

In this team design challenge (page 11-18 of PDF), learners design and build a Landing Pod for a model Lunar Rover (previously built in activity on page 1-10 of PDF).

In this activity, learners build bridges and cantilevers in a series of "building out" challenges with straws and pins.

In this hands-on activity, learners investigate the functional design of leaves on a tree.

This activity (on page 2 of the PDF under SciGirls Activity: Luge) is a full inquiry-based challenge related to motion and design optimization.

In this activity, learners create 3D geometric shapes using straws and pipe cleaners.

Learners explore the field of civil engineering by making a bridge using spaghetti as their primary building material.

This activity (on pages 19-24) introduces learners to the rain forest's layers—emergent, canopy, understory, and forest floor—and has learners make paper lianas (vines that live attached to trees) and

Learners follow directions to construct a water-powered electrical generator using a turbine made from plastic spoons.