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In this activity about living things and gravity (page 5 of PDF), learners design and build an exoskeleton or an endoskeleton for an animal of their own invention.

In this activity about endoskeletons (page 8 of PDF), learners observe, compare and contrast different kinds of chicken bones, and relate their chicken bone observations to human bones.

In this activity (page 89 of the PDF), learners compare and contrast pitch and roll motions by using a Magic Carpet maze similar to one that was used for Neurolab investigations about microgravity.

The Butterflies in Space Teacher's Guide uses "life in space" to encourage learners to conduct their own open-ended scientific investigations.