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Learners observe a model of a cell and its chromosomal DNA made from a plastic egg and dental floss. Use this model to illustrate how much DNA is held in one cell.

In this team design challenge (page 19-24 of PDF), learners "land" a model Lunar Rover in a model Landing Pod (both previously built in activities #3 and #4 in PDF).

In this lesson, learners develop a robot arm using common materials. Learners explore design, construction, and teamwork, as well as materials selection and use.

In this activity on page 3 of the PDF, learners visualize the relative size and structural differences between microbes that have the potential to cause disease.

In this activity, learners simulate nature's water filtration system by devising a system that will filter out both visible and invisible pollutants from water.

In this team design challenge (page 2-10 of PDF), learners design and build a model of a Lunar Transport Rover that will carry equipment and people on the surface of the Moon.

In this team design challenge (page 11-18 of PDF), learners design and build a Landing Pod for a model Lunar Rover (previously built in activity on page 1-10 of PDF).

In this activity, learners build bridges and cantilevers in a series of "building out" challenges with straws and pins.

In this hands-on activity, learners investigate the functional design of leaves on a tree.

This activity (on page 2 of the PDF under SciGirls Activity: Luge) is a full inquiry-based challenge related to motion and design optimization.

In this activity, learners create 3D geometric shapes using straws and pipe cleaners.

In this activity, learners explore how genetic switches function and the role of genetic switches in the process of evolution.

In this activity, learners take measurements and create charts to learn about the size of dinosaurs and their relative scale to humans.

Learners explore the field of civil engineering by making a bridge using spaghetti as their primary building material.

In this activity, learners explore dinosaurs and fossils by creating a diorama.

In this activity (page 4 of the pdf), learners build a model of a tide pool, using chicken wire, paper mache, and other craft materials.

Learners follow directions to construct a water-powered electrical generator using a turbine made from plastic spoons.

In this activity, learners explore work, forces, simple machines, and construction. This lesson guide includes simple ways to demonstrate these principles as well as hands-on activities.