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This activity (on page 2 of the PDF under SciGirls Activity: Malformed Frogs) is a full inquiry investigation into using indicator species to assess the health of an environment.

In this activity (page 7 of pdf), learners research tide pool ecosystems, and then create brochures that "advertise" these environments.

The Butterflies in Space Teacher's Guide uses "life in space" to encourage learners to conduct their own open-ended scientific investigations.