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Respiration Relay
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In this physical activity, groups of learners act as blood cells traveling through the circulatory system.

Raising the Level of Carbon Dioxide in Your Blood
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In this activity (on page 146 of the PDF), learners will explore the effects of increased carbon dioxide in the bloodstream.

What Goes Around Comes Around
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In this simulation activity, learners act as parts of the circulatory system and discover how it serves as a transport system for food/nutrients, oxygen, carbon dioxide and waste.

How Long Can You Hold Your Breath?
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In this activity (on page 142 of the PDF), learners will compare breathing rates before and after hyperventilation to explore how reduced carbon dioxide levels in the blood lower the need to breathe.

Circulatory System Skit: Act out the Flow of Blood
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In this activity, learners act out the flow of blood in the human body! A great way to get learners up and moving while learning about the circulatory system.