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In this activity, learners use a flexible magnet as a model for a scanning probe microscope (SPM). They learn that SPMs are an example of a special tool that scientists use to work on the nanoscale.

In this activity, learners make slides of onion cells and their own cheek cells. Use this lab to teach learners how to prepare microscope slides and use a microscope.

In this activity, learners describe an object they can’t see. After someone picks outs a few mystery objects and places them in a pillowcase, learners will investigate using only their hands.

In this activity, learners use coverslips to collect organisms from a pond, estuary or marine environment and then examine what they have caught with a microscope.

In this geology activity, learners use a microscope to discover and identify the components of sand.

In this activity, learners use Styrofoam to collect organisms from a pond, estuary or marine environment and then examine what they have caught with a microscope.

In this activity, learners try to put together toy bricks—wearing oven mitts on their hands! This activity shows learners how difficult it is to build small things when your tools are too big.

In this activity on page 1 of the PDF, learners compare the relative sizes of biological objects (like DNA and bacteria) that can't be seen by the naked eye.

This activity uses Jell-O(R) to introduce learners to microfluidics, the flow of fluids through microscopic channels.

This exercise can be used to stimulate the investigative nature of learners as they use forensic plant pathology techniques to prove the learners' innocence in a mock murder investigation.

In this fun sticker activity, learners will create a size wheel with images of objects of different size, from macroscopic scale (like an ant) to nanoscale (like DNA).

This simple activity uses paper and scissors to convey two key concepts to learners: the nanoscale is very small and working on the nanoscale requires special tools.

In this activity, learners place cards featuring biological structures in order by their relative size from largest to smallest.

In this activity, learners build a LEGO® structure while wearing mittens. This activity shows learners how difficult it is to build small things when your tools are too big.

In this activity about scale, learners investigate the world of the very small by cutting a 28 centimeter strip of paper in half as many times as they can.

In this activity (page 37 of the PDF), learners observe, on a prepared slide, muscle and spinal cord cells from a rat.

In this activity, learners create a sealed, mini ecosystem that supplies freshwater shrimp with food, oxygen, and waste processing for at least three months.

This demonstration can be used to help learners visualize DNA by lysing (breaking open) bacterial cells on a slide and “stringing up” the DNA with a toothpick in less than one minute.

In this laboratory activity, learners use a simple procedure to bait oomycetes from water and/ or soil and then examine these fungus-like organisms with the microscope to see how they look.