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In this activity (on page 142 of the PDF), learners will compare breathing rates before and after hyperventilation to explore how reduced carbon dioxide levels in the blood lower the need to breathe.

In this activity about how the body regulates blood pressure (page 117 of the PDF), learners make and compare measurements of heart rate and blood pressure from three body positions: sitting, standing

In this activity (on page 146 of the PDF), learners will explore the effects of increased carbon dioxide in the bloodstream.

In this activity, learners explore how eating unhealthy food can damage a heart and arteries.

In this experiment, pairs of learners explore how cold water affects circulation. The mammalian diving reflex (MDR) slows circulation when the body is exposed to cold water.