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Make a DNA Model
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In this activity, learners make a 3-D model of DNA using paper and toothpicks. While constructing this model, learners will explore the composition and structure of DNA.

Aviary Architect
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In this activity, learners are challenged to design, build and test a birdhouse that will stay cool in the sun.

Conduction Countdown
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In this quick SciGirls activity (page 1 of the PDF under SciGirls Activity: Doghouse Design), learners will be introduced to the concept of thermal conductivity.

Measuring Earthquakes
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In this activity, learners build their your own seismograph with household materials to document shaking.

Finger Knitting
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In this activity, learners will learn how to knit using only their hands. Learners will explore patterns and fabrication as well as develop fine motor skills and patience through this activity.

Egg Bungee
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Learners attach an egg to a rubber-band bungee cord and drop the egg.

Kinetic Sculpture
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In this design challenge activity, learners build a tower that’s at least 12 inches high with two or more parts that move (spin, sway, or flap) in the wind.

Blink
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In this self-measuring activity, learners observe and record how many times a minute they blink, take a breath, and chew, as well as how many times a minute their heart beats.

Where the Buffalo Roam
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In this activity, learners explore the Great Plains.

Sustainable Fishing
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In this activity, learners use a model for how fishing affects marine life populations, and will construct explanations for one of the reasons why fish populations are declining.

Cut-Fold-Staple
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In this activity, learners discover how to rotate a flat shape into the third dimension. Learners draw and cut out a shape that has at least one straight edge on an index card.

Lava Layers
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In this activity (on pages 11-12 of PDF) learners create models of lava layers that have formed on the moon.

Nano Latch-n-Catch
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In this activity, learners design a therapeutic agent to image and/or cure various diseases in the respiratory system.

Get In The Game
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In this design challenge, learners will use computational thinking to design their own board game.

Sound Representation: Modems Unplugged
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In this activity, learners listen to songs and decode hidden messages based on the same principle as a modem. As a final challenge, learners decode the binary messages in a music video.

Color Code
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In this activity, learners conduct the "Stroop Effect" test and explore what happens when they try to complete two simple tasks at the same time.

Are Microbes Alive?
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In this activity (on pages 19-21 of the PDF) learners observe mold growing on potatoes. Preparation for this activity has to start a week before, to allow time for the mold to grow on the potatoes.
Shadow Puppets
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If you have lights, cardboard, scissors, and some brass fasteners, you can make shadow puppets! Create a story-telling and design challenge for your learners with this simple and creative activity.

Zip Line
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In this design challenge activity, learners build a device to carry a Ping-Pong ball from the top of a zip line to the bottom in four seconds (or less!).

Hieroglyph Holiday
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In this activity about archaeology, learners will explore different Egyptian hieroglyphs and recognize their meanings and uses.