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Crossing the Synaptic Gap
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In this neuroscience activity, learners conduct a simulation to demonstrate how multiple incoming signals influence the action of neurons.

Modeling Day and Night
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In this activity (on page 1 of the PDF), learners make a "mini-globe" to investigate the causes of day and night on our planet.

The Geophysical Light/Dark Cycle
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This is an activity (located on page 131 of the PDF) related to sleep and circadian rhythms as well as space travel.

Baroreceptor Reflex Role Play
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In this activity about the baroreceptor reflex (BR) arc (page 123 of the PDF), learners discover the importance of maintaining adequate arterial blood pressure through a role playing exercise.

Skin Deep
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In this activity, learners explore how to protect their skin while applying pesticides to plants.
Mercury in the Environment
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In this environmental science lesson, learners will examine the dangers of mercury and how humans contribute to growing mercury emissions on Earth.

Adherence to HIV Treatment
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In this activity, learners simulate taking HIV antiretroviral drugs by using Tic Tac mints and Kool-Aid packets.

Rumination
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In this activity (on pages 24-34), learners explore the four-part stomach of cows (and other grazing animals called ruminants), and compare it to the human one-part stomach and its digestive process.

Grabbing a Bite to Eat
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In this activity, learners perform an experiment that replicates the dilemma faced by birds in acquiring food from a confined area.

Shape Up!
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In this activity (25th on the page) about learning and memory, learners explore a training method that animal trainers employ called "shaping." Working in pairs, learners will attempt to "shape" each

Synaptic Tag
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In this outdoor activity, learners review the parts of the synapse and their functions by playing a game.

The Game of Life: Stem Cell Edition
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In this activity, learners play a game that models what happens as stem cells differentiate into different cell types.

Get a Leg Up
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In this activity, learners experiment and collect data during a simulation of the fluid shifts experienced by astronauts' bodies in microgravity.

Jump for the Moon
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In this activity, learners will train to increase bone strength and to improve heart and other muscle endurance by performing jump training with a rope, both while stationary and moving.

As The Stomach Churns
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In this chemistry activity, learners fill two test tubes with a solution of "artificial stomach fluid," consisting of hydrochloric acid in the same concentration as in human stomachs, some soap to cre

Antigen-Antibody Testing: A Visual Simulation or Virtual Reality
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In this biology activity, learners use plastic pipettes to cut wells into the solid gel layer of agar in petri dishes and place solutions of simulated antigen and antibody preparations into the wells.

Variation Game
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In this set of outdoor games, learners play the role of monkeys that are trying to get enough resources (food, shelter, and space) to survive.

Forensic Science: Hair Sample Investigation
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This activity (on page 2 of the PDF under SciGirls Activity: Forensics) is a full inquiry investigation into how hairs from a crime scene are matched to suspects.

Pom Pom Potential
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In this kinesthetic activity, learners move pom-pom "ions" across a membrane to simulate how an action potential is propagated along an axon.

Jumpin' the Gap
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In this simulation of synapses, learners act out communication at the neural level by behaving as pre-synaptic vesicles, neurotransmitters, post-synaptic receptors, secondary messengers and re-uptake