Stem Cell Differentiation Game

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This game uses a modified Uno deck to review concepts related to stem cell research and diabetes. Specifically, it covers material in the "Pulse-Chase Primer," "Pancreatic Beta Cells," and "Microarrays and Stem Cells" activities from the same resource which may or may not be necessary to complete prior to this activity (depending on learner's prior knowledge). Learners accumulate points and answer questions about stem cells, development, and microarrays so that they can be the first to differentiate into a pancreatic beta (β) cell. This activity is recommended for learners studying Biology at the High School (honors, IB and AP) or Undergraduate level.

Quick Guide

Preparation Time:
5 to 10 minutes

Learning Time:
30 to 45 minutes

Estimated Materials Cost:
$1 - $5 per group of students

Age Range:
Ages 14 - adult

Resource Types:
Activity, Game, Lesson/Lesson Plan


Materials List (per group of students)


  • Engineering and Technology
    • Engineering
      • Bioengineering/Biomedical Engineering
  • Life Sciences
    • Cells
      • Cell Structure and Function
    • Heredity and Genetics
      • Human Genetics
      • DNA Structure and Function
      • Genetic Engineering
    • Human Body
      • Digestion
      • Health and Nutrition
      • Medicine
      • Immune System
  • Physical Sciences
    • Chemistry
      • Chemistry of Life
  • The Nature of Science
    • Science and Society
      • Risks and Benefits
    • Science as a Career
  • The Nature of Technology
    • The Design Process
      • Research and Development

Informal Categories

  • Games


To use this activity, learners need to:

  • see
  • see color
  • read
  • touch

Learning styles supported:

  • Involves hands-on or lab activities


Components that are part of this resource:

This resource is part of:

Access Rights:

  • Free access


  • Colvard, Mary


  • All rights reserved, Howard Hughes Medical Institute, 2010