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DNA Extraction
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In this activity related to plant biotechnology, learners extract DNA from fruit to investigate how it looks and feels.
Let's Clone a Mouse, Mouse, Mouse...
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Somatic Cell Nuclear Transfer (SCNT) is a cloning method that involves transferring a nucleus from a somatic cell of the individual to be cloned to an enucleated egg.
Animal & Plant Cell Slides
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In this activity, learners make slides of onion cells and their own cheek cells. Use this lab to teach learners how to prepare microscope slides and use a microscope.
Modeling Limits to Cell Size
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This investigation provides learners with a hands-on activity that simulates the changing relationship of surface areas-to-volume for a growing cell.
Transformation of E. coli Using Green Fluorescent Protein
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In this activity related to plant biotechnology, learners transform a strain of E. coli using green fluorescent protein from a bioluminescent jellies.
DNA the Easy Way
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This demonstration can be used to help learners visualize DNA by lysing (breaking open) bacterial cells on a slide and “stringing up” the DNA with a toothpick in less than one minute.
Collaboration via Slime Mold
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In this highly collaborative activity, learners design and complete a controlled experiment which attempts to answer a simple question about the slime mold Physarum.
Pathways with Friends
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Directed by instructional cards, learners kinesthetically model cell communication by acting as components in a cell signaling pathway.
Diffusion & Osmosis with Data Analysis
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This three-part lab helps learners understand the essential principles governing diffusion and osmosis.
Stem Cell Differentiation Game
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This game uses a modified Uno deck to review concepts related to stem cell research and diabetes.
Modeling an HIV Particle
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This activity helps learners visualize the Human Immunodeficiency Virus (HIV) by constructing three-dimensional HIV particle models from paper.
What Cells Can I See in Muscle and Spinal Cord Tissues?
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In this activity (page 37 of the PDF), learners observe, on a prepared slide, muscle and spinal cord cells from a rat.
The Jelly Bean Problem (JBP)
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In this activity, learners are challenged to eat some candy as a cell would need to as well as to think about some of the problems that arise when a cell ingests food.
Coffee to Carbon
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In this activity, learners place cards featuring biological structures in order by their relative size from largest to smallest.
Dealing Signals
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In this activity, use standard playing cards to introduce learners to cellular interactions such as cell to cell recognition and signal and receptor specificity.
Microarrays and Stem Cells
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In this activity, learners use microarray technology to determine which genes are turned on and off at various points in the differentiation of pluripotent stem cells on their way to becoming pancreat
Using Bubbles to Explore Membranes
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In this activity, learners use bubbles to investigate the structure and unique properties of cell membranes. Bubbles serve as macroscopic models that mimic the cells' phospholipid bilayers.
Build-A-Membrane
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In this activity, learners cut, fold, and paste paper representing biomolecules to create a three-dimensional cell membrane with embedded proteins.