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Learners observe a model of a cell and its chromosomal DNA made from a plastic egg and dental floss. Use this model to illustrate how much DNA is held in one cell.

This marine biology activity (on pages 11-17) introduces learners to kelp (seaweed) forests that grow in the ocean and are home to many species of sea animals.

In this detailed activity (on pages 9-18), learners investigate the body parts of a parasitic ascaris worm by making and dissecting clay models.

In this activity, learners explore how salt water freezes in comparison to fresh water.

In this activity, learners simulate nature's water filtration system by devising a system that will filter out both visible and invisible pollutants from water.

In this activity about engineering, nutrition, and physical activity, learners design and build a healthy bone model of a space explorer which is strong enough to withstand increasing amounts of weigh

In this activity about living things and gravity (page 5 of PDF), learners design and build an exoskeleton or an endoskeleton for an animal of their own invention.

In this activity, learners construct a model of DNA to better understand the structure of DNA and protein synthesis.

In this hands-on activity, learners investigate the functional design of leaves on a tree.

In this activity (on pages 30-36), learners simulate a dig for ancient pollen, to experience how paleobotanists study fossilized pollen in rocks to learn about early geological and climatological even

This activity helps learners visualize the Human Immunodeficiency Virus (HIV) by constructing three-dimensional HIV particle models from paper.

In this activity, (on page 6 of the PDF under SciGirls Activity: Dinosaurs) learners participate in a hands-on fossil excavation.

In this activity, learners take measurements and create charts to learn about the size of dinosaurs and their relative scale to humans.

This activity (on pages 24-29) combines science and art to introduce learners to how different animal pollinators spread pollen from one plant to another, and how certain shapes, colors, and smells of

This activity (on pages 13-18) has learners build a model tree and then figure out how to make their tree stand up by itself.

In this activity (page 4 of the pdf), learners build a model of a tide pool, using chicken wire, paper mache, and other craft materials.

This activity (on pages 19-24) introduces learners to the rain forest's layers—emergent, canopy, understory, and forest floor—and has learners make paper lianas (vines that live attached to trees) and

Educator Amy O'Donnell from the American Museum of Natural History guides learners to create a diorama of a coral reef.

This activity (located on page 4 of the PDF under GPS: Baby Dinosaurs Activity) is a full inquiry investigation to determine the age of fossils based on where they are discovered.

In this genetics activity, learners create imaginary creatures known as "Reebops" to explore the relationships between genes and inherited traits.