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Lean, Mean Information Machine: Using a Simple Model to Learn about Chromosomal DNA
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Learners observe a model of a cell and its chromosomal DNA made from a plastic egg and dental floss. Use this model to illustrate how much DNA is held in one cell.

Small Worlds
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This is a simple activity fully driven by imagination. Using materials from the home, toys, or items from nature, learners create their own world to play with.

Modeling Day and Night
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In this activity (on page 1 of the PDF), learners make a "mini-globe" to investigate the causes of day and night on our planet.

From Polliwog to Frog
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In this activity, learners discover how frogs' bodies change while growing from a tadpole to a frog. Learners create a simple craft that gives a visual display of the metamorphosis process.

How Do Viruses Recognize a Target Cell?
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This activity demonstrates the specificity of viral vectors for target cells in gene therapy delivery methods using two approaches: 1) STYROFOAM® models demonstrate viral ligand binding to receptor pr

Drain Game
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In this activity (on pages 36-39), learners make a model of a watershed out of paper, then run water down the mountain to simulate how rainfall and pollution affect watersheds.

Have a Heart
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Your heart pumps blood throughout your body in one direction, around in a loop. In this activity, learners will make a model of one type of heart chamber called a ventricle.

Straining Out the Dirt
Learners take on the role of environmental engineers as they design water filters.

Modeling Limits to Cell Size
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This investigation provides learners with a hands-on activity that simulates the changing relationship of surface areas-to-volume for a growing cell.

Water Clean-up
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This is an activity (located on page 3 of the PDF under Water Clean-up Activity) about the use of reduction agents to decontaminate ground water.

Space Stations: Bones of Contention
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In this activity, learners make models representing bones on Earth and bones that have been in space. They discover what happens to bones without proper exercise and nutrition.

Space Stations: Sponge Spool Spine
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In this activity, learners simulate what happens to a human spine in space by making Sponge Spool Spines (alternating sponge pieces and spools threaded on a pipe cleaner).

DNA Modeling Activity
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Using pipe cleaners, straws, and beads, learners explore the building blocks of life by creating their own model of DNA.

Fossils: Observing, Making and Learning
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In this activity, learners explore how casts of fossilized bones are created and used to learn about dinosaurs. Learners make observations, draw diagrams and share their findings.

Lung Capacity
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This is an activity about lung capacity. Learners will measure their own lung capacity using a homemade spirometer.

Make a Dinosaur Model
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In this activity, learners explore dinosaur skeletons, anatomy, and locomotion. Learners compare and contrast dinosaur skeletons and drawings.

Invent an Insect
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In this creative activity, learners will find out what makes an insect an insect by studying examples of insect adaptations and by examining why there are so many different types of insects.

Life Size: What's in a microbe?
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In this activity on page 3 of the PDF, learners visualize the relative size and structural differences between microbes that have the potential to cause disease.

Clean Water: Is It Drinkable?
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In this activity, learners simulate nature's water filtration system by devising a system that will filter out both visible and invisible pollutants from water.

Yummy Gummy Double Helix
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In this activity, learners make their own edible DNA double helix out of candy and find out about the shape of DNA.