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Lean, Mean Information Machine: Using a Simple Model to Learn about Chromosomal DNA
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Learners observe a model of a cell and its chromosomal DNA made from a plastic egg and dental floss. Use this model to illustrate how much DNA is held in one cell.

Modeling Day and Night
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In this activity (on page 1 of the PDF), learners make a "mini-globe" to investigate the causes of day and night on our planet.

How Do Viruses Recognize a Target Cell?
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This activity demonstrates the specificity of viral vectors for target cells in gene therapy delivery methods using two approaches: 1) STYROFOAM® models demonstrate viral ligand binding to receptor pr

Modeling Limits to Cell Size
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This investigation provides learners with a hands-on activity that simulates the changing relationship of surface areas-to-volume for a growing cell.

Water Clean-up
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This is an activity (located on page 3 of the PDF under Water Clean-up Activity) about the use of reduction agents to decontaminate ground water.

Space Stations: Bones of Contention
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In this activity, learners make models representing bones on Earth and bones that have been in space. They discover what happens to bones without proper exercise and nutrition.

Space Stations: Sponge Spool Spine
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In this activity, learners simulate what happens to a human spine in space by making Sponge Spool Spines (alternating sponge pieces and spools threaded on a pipe cleaner).

As Straight as a Pole
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In this engineering activity (page 3 of PDF), young learners investigate how a pole can be made stable by “planting” its base in the ground or adding supports to the base.

Stream Table
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In this activity, learners use aluminum trays and wooden blocks to form stream tables to investigate river formations in two different landscape scenarios.

Mars from Above: Carving Channels
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In this activity, learners create channel features with flowing water, comparing their observations to real images of Mars and Earth taken by satellites/orbiters.

Biodomes Engineering Design Project
In this design-based activity, learners explore environments, ecosystems, energy flow and organism interactions by creating a model biodome. Learners become engineers who create model ecosystems.

Building a 3-D Space Maze: Escher Staircase
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In this activity (page 95 of the PDF), learners create Escher Staircase models similar to those that were used by Neurolab's Spatial Orientation Team to investigate the processing of information about

Supporting Structures
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In this activity about living things and gravity (page 5 of PDF), learners design and build an exoskeleton or an endoskeleton for an animal of their own invention.

The Great Plankton Race
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In this activity, learners are challenged to design a planktonic organism that will neither float like a cork nor sink like a stone.

Earth Atmosphere Composition
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In this activity, learners use rice grains to model the composition of the atmosphere of the Earth today and in 1880. Learners assemble the model while measuring percentages.

Solar Water Heater
Learners work in teams to design and build solar water heating devices that mimic those used in residences to capture energy in the form of solar radiation and convert it to thermal energy.

Human Impact on Estuaries: A Terrible Spill in Grand Bay
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In this activity, learners make a model of a pollution spill that occurred at Bangs Lake in Mississippi and measure water quality parameters in their model.

Molecular Menagerie
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In this activity, learners use molecular model kits to construct familiar molecules like lactose, caffeine, and Aspirin.

Make Your Own Deep-Sea Vent
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In this activity, learners make a model of the hot water of a deep sea vent in the cold water of the ocean to learn about one of the ocean's most amazing and bizarre underwater habitats.

Size, Scale and Models
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In this activity, learners take measurements and create charts to learn about the size of dinosaurs and their relative scale to humans.