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Lean, Mean Information Machine: Using a Simple Model to Learn about Chromosomal DNA
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Learners observe a model of a cell and its chromosomal DNA made from a plastic egg and dental floss. Use this model to illustrate how much DNA is held in one cell.

Small Worlds
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This is a simple activity fully driven by imagination. Using materials from the home, toys, or items from nature, learners create their own world to play with.

Modeling Day and Night
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In this activity (on page 1 of the PDF), learners make a "mini-globe" to investigate the causes of day and night on our planet.

From Polliwog to Frog
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In this activity, learners discover how frogs' bodies change while growing from a tadpole to a frog. Learners create a simple craft that gives a visual display of the metamorphosis process.

How Do Viruses Recognize a Target Cell?
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This activity demonstrates the specificity of viral vectors for target cells in gene therapy delivery methods using two approaches: 1) STYROFOAM® models demonstrate viral ligand binding to receptor pr

Drain Game
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In this activity (on pages 36-39), learners make a model of a watershed out of paper, then run water down the mountain to simulate how rainfall and pollution affect watersheds.

Have a Heart
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Your heart pumps blood throughout your body in one direction, around in a loop. In this activity, learners will make a model of one type of heart chamber called a ventricle.

Straining Out the Dirt
Learners take on the role of environmental engineers as they design water filters.

Modeling Limits to Cell Size
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This investigation provides learners with a hands-on activity that simulates the changing relationship of surface areas-to-volume for a growing cell.

Water Clean-up
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This is an activity (located on page 3 of the PDF under Water Clean-up Activity) about the use of reduction agents to decontaminate ground water.

Space Stations: Bones of Contention
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In this activity, learners make models representing bones on Earth and bones that have been in space. They discover what happens to bones without proper exercise and nutrition.

DNA Modeling Activity
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Using pipe cleaners, straws, and beads, learners explore the building blocks of life by creating their own model of DNA.

Space Stations: Sponge Spool Spine
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In this activity, learners simulate what happens to a human spine in space by making Sponge Spool Spines (alternating sponge pieces and spools threaded on a pipe cleaner).

Fossils: Observing, Making and Learning
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In this activity, learners explore how casts of fossilized bones are created and used to learn about dinosaurs. Learners make observations, draw diagrams and share their findings.

Lung Capacity
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This is an activity about lung capacity. Learners will measure their own lung capacity using a homemade spirometer.

Make a Dinosaur Model
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In this activity, learners explore dinosaur skeletons, anatomy, and locomotion. Learners compare and contrast dinosaur skeletons and drawings.

As Straight as a Pole
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In this engineering activity (page 3 of PDF), young learners investigate how a pole can be made stable by “planting” its base in the ground or adding supports to the base.

Stream Table
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In this activity, learners use aluminum trays and wooden blocks to form stream tables to investigate river formations in two different landscape scenarios.

Mars from Above: Carving Channels
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In this activity, learners create channel features with flowing water, comparing their observations to real images of Mars and Earth taken by satellites/orbiters.

Dinosaur Homes
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In this activity about dinosaurs and survival, learners use scrap materials to create a miniature dinosaur habitat that includes a food source, water source, and shelter.