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Lean, Mean Information Machine: Using a Simple Model to Learn about Chromosomal DNA
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Learners observe a model of a cell and its chromosomal DNA made from a plastic egg and dental floss. Use this model to illustrate how much DNA is held in one cell.

Let's Clone a Mouse, Mouse, Mouse...
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Somatic Cell Nuclear Transfer (SCNT) is a cloning method that involves transferring a nucleus from a somatic cell of the individual to be cloned to an enucleated egg.

DNA Detective
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This activity is about collecting and analyzing DNA as part of a criminal investigation.

Fingerprints
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In this activity, learners examine their fingerprints and learn that they can be categorized by shape, but each fingerprint is unique.

Origami DNA
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In this activity, learners create an origami model of DNA, demonstrating its double helix structure.

Viral Packaging
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In this activity, learners create virus models, including nucleic acid and proteins, using simple materials. This resource includes information about virus structure and gene therapy.

DNA Extraction: Look at your genes!
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Extract your DNA from your very own cells! First, learners swish salt water in their mouth to collect cheek cells and spit the water into a glass.

An Inventory of My Traits
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In this genetics meets math activity, learners take inventories of their own easily-observable genetic traits and compare those inventories with other learners in groups.

Breakfast Proteins
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In this activity, learners construct a cereal chain as a model of how proteins are made in the cell.

Close, Closer, Closest
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In this activity, learners perform an experiment that models a chromatography-like process called electrophoresis, a process used to analyze DNA.

Multifactorial Inheritance
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In this biology activity (page 6 of the PDF), learners roll a die to create a simple model that teaches them about the factors contributing to heart disease.

Risk Continuum
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This activity is a whole-group kinesthetic demonstration that shows learners what it means to be in a "risk group" for developing heart disease based on family history and genetics.

Handy Family Tree
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In this bilingual (English/Spanish) activity, learners create family trees by tracing the hands of their family members.

Yabba-Dabba You
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In this activity, learners explore genes and traits. Learners investigate their fingerprints and learn how to categorize them.

Phylogenetics
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This activity lets learners participate in the process of reconstructing a phylogenetic tree and introduces them to several core bioinformatics concepts, particularly in relation to evolution.

Wear a Chimp on Your Wrist
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Learners construct a bracelet containing two strands of beads, which represents a double strand of DNA that codes for a gene. They match beads to the bases in a section of a chimp's DNA code.

What Sort?
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In this activity (on pages 22-33), learners do the kind of work genetic scientists do, sorting and comparing (images of) genetic material strands called chromosomes.

Microarrays and Stem Cells
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In this activity, learners use microarray technology to determine which genes are turned on and off at various points in the differentiation of pluripotent stem cells on their way to becoming pancreat

Size Wheel
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In this fun sticker activity, learners will create a size wheel with images of objects of different size, from macroscopic scale (like an ant) to nanoscale (like DNA).

What's the Risk?
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To discover the risk and protective factors involved in substance addiction, learners play a game of chance to determine whether a fictitious child is likely or unlikely to abuse drugs.