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Tiny Particles, Big Trouble!
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In this activity, learners discover why some nanoscale science and technology is done in the controlled environment of a clean room, what clean rooms are like, and how scientists help keep the clean r

Plugged in to CO2
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In this activity, learners investigate various appliances and electronics, discovering how much energy each uses and how much carbon dioxide (CO2) is released to produce that energy.

Composting
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In this environmental science activity, learners research what is essential for plant life and the necessary components of soil to support plants.

Plant Tissue Culture: Classroom Activities in Plant Biotechnology
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In this activity related to plant biotechnology, learners use the tissue culture process to rapidly produce clones (genetic copies) of a particular plant (cauliflower, rose cuttings, African violet le

Gel Electrophoresis
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In this activity, learners simulate the process of DNA fingerprinting by using electricity to separate colored dyes.

Does Sunscreen Protect My DNA?
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In this laboratory experiment, learners explore how effectively different sunscreens protect yeast cells from damage caused by ultraviolet (UV) radiation.

Planting with Precision
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In this activity, learners explore how engineers work to solve the challenges of a society, such as efficient planting and harvesting.

Forensic Science: Hair Sample Investigation
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This activity (on page 2 of the PDF under SciGirls Activity: Forensics) is a full inquiry investigation into how hairs from a crime scene are matched to suspects.

Clap Sensor: Build a Sound Sensor Using a Pico Cricket
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This activity requires a Pico Cricket (tiny computer). Learners work on designing and building a sound sensor out of household materials, like plastic wrap and cardboard.

Glass and Mirrors: An Inside Look at Telescopes
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This hands-on astronomy activity allows you to create a “cutaway” telescope to clearly show how reflector and refractor telescopes work.

Plankton Races
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In this two-part activity, learners investigate buoyancy, density and surface area as well as biodiversity and the relationship between the structure and function of organisms.

Disease Detectives
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In this activity, learners examine antibodies and antibody recognition using a model.

Slimy Cells
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In this activity, learners solidify their conceptualization of cells by building a model of a cell in a ziplock bag.

Nano Latch-n-Catch
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In this activity, learners design a therapeutic agent to image and/or cure various diseases in the respiratory system.

Heart of the Matter
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In this activity, learners explore the concept of valve operation and how engineers have adapted valves for use in mechanical heart valve design.

Oil Spill Solutions
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In this activity, learners explore how environmental engineers might approach solving the problem of an oil spill.
What Does Life Need to Live?
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In this astrobiology activity (on page 11 of the PDF), learners consider what organisms need in order to live (water, nutrients, and energy).

Simulation of Laparoscopic Surgery Lab
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This simulation of laparoscopic surgery enables learners to practice and to learn this modern surgical technique.

Racing with the Sun: Creating a Solar Car
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Learners use engineering design principles to construct and test a fully solar-powered car. Solar car kits usually include a photovoltaic cell and motor; some include a chassis as well.

Home Mycology Lab
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Agriculturalists have long considered mushroom growing a challenge, largely because you need a piece of benchtop equipment known as a laminar flow hood.