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Lean, Mean Information Machine: Using a Simple Model to Learn about Chromosomal DNA
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Learners observe a model of a cell and its chromosomal DNA made from a plastic egg and dental floss. Use this model to illustrate how much DNA is held in one cell.

Modeling Day and Night
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In this activity (on page 1 of the PDF), learners make a "mini-globe" to investigate the causes of day and night on our planet.

Modeling Limits to Cell Size
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This investigation provides learners with a hands-on activity that simulates the changing relationship of surface areas-to-volume for a growing cell.

Water Clean-up
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This is an activity (located on page 3 of the PDF under Water Clean-up Activity) about the use of reduction agents to decontaminate ground water.

Thinking in Three Dimensions
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In this activity, learners create three-dimensional shapes by making some origami models of simple boxes and containers.

Space Stations: Sponge Spool Spine
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In this activity, learners simulate what happens to a human spine in space by making Sponge Spool Spines (alternating sponge pieces and spools threaded on a pipe cleaner).

Make a Dinosaur Model
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In this activity, learners explore dinosaur skeletons, anatomy, and locomotion. Learners compare and contrast dinosaur skeletons and drawings.

Life Size: What's in a microbe?
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In this activity on page 3 of the PDF, learners visualize the relative size and structural differences between microbes that have the potential to cause disease.

Living Bones, Strong Bones
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In this activity about engineering, nutrition, and physical activity, learners design and build a healthy bone model of a space explorer which is strong enough to withstand increasing amounts of weigh

Earth's Water: A Drop in Your Cup
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This creative lesson plan provides a visual way for learners to gain knowledge about the finite amount of fresh water on Earth and encourages the discussion of the various ways to conserve this resour

Cell Division
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This activity was designed for blind learners, but all types of learners can use it to investigate how, in a one-celled organism such as a bacterium, the division of cells increases the number of cell

Make a Terrarium
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In this activity, learners make a miniature greenhouse or "terrarium" to explore the greenhouse effect.

Biobarcodes: Antibodies and Nanosensors
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In this activity/demo, learners investigate biobarcodes, a nanomedical technology that allows for massively parallel testing that can assist with disease diagnosis.

Evolution in Plane Sight
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In this activity, learners model directed evolution by making paper fly. Learners construct and fly paper airplanes.

Visualizing How the Vestibular System Works
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In this activity (page 59 of the PDF), learners spin and observe false eyelashes in jars of water (prepared at least 1 day ahead of time) to investigate the effects of different types of motion on the

Shoe Dichotomous Key
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In this activity (on page 2 of the PDF under GPS: Cactus Activity), learners will develop their own version of a tool used by biologists, a dichotomous key, by collecting all their left shoes.

Traveling Nanoparticles Model
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This is an activity (located on page 3 of the PDF under Nanosilver Activity) about diffusion of small molecules across cell membranes.

Plankton Feeding
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This activity provides a hands-on experience with a scale model, a relatively high viscosity fluid, and feeding behaviors.
Plants: Hanging Tough
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In this hands-on activity, learners will become familiar with the special adaptations of rainforest plants and discover the conditions needed for tropical trees to survive along with what can impinge
Leaves: Designing Leaf Arrangements on a Branch
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In this hands-on activity, learners investigate the functional design of leaves on a tree.