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Candy Dish Natural Selection
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In this yummy biology activity (page 3 of the PDF), learners participate in a demonstration of natural selection.

Make a DNA Model
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In this activity, learners make a 3-D model of DNA using paper and toothpicks. While constructing this model, learners will explore the composition and structure of DNA.

Colorful Electrophoresis
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In this activity, learners follow step-by-step instructions to build a gel electrophoresis chamber using inexpensive materials from local hardware and electronic stores.

Chromosome Models: Karyotyping
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This activity was designed for blind learners, but all types of learners can have a tactile opportunity to construct a karyotype, an organized model of an organism’s chromosomes, conveying the chromos

String Genome
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In this biology activity (page 5 of the PDF), learners use yarn and sticky labels to build a model of a DNA strand. They discover that DNA is very long, very skinny, and packs well into cells.

DNA and Histone Model
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In this activity, learners construct a 3-D paper model depicting how histone, acetyl and methyl molecules control access to DNA and affect gene DNA expression.

Macromodel of Microarray
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This is an educator-led demonstration of microarray technology using a model created from a pizza box and ping-pong balls.

Wear a Chimp on Your Wrist
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Learners construct a bracelet containing two strands of beads, which represents a double strand of DNA that codes for a gene. They match beads to the bases in a section of a chimp's DNA code.

Alike and Different
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This activity (on pages 7-13) has pairs of learners survey an array of similarities and differences between them.

Transformation of E. coli Using Green Fluorescent Protein
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In this activity related to plant biotechnology, learners transform a strain of E. coli using green fluorescent protein from a bioluminescent jellies.

Make Your Own DNA
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Learners match puzzle pieces to outlines of a DNA strand. The puzzle pieces represent the four chemicals making up DNA base pairs: adenine, thymine, guanine, and cytosine.

Have Your DNA and Eat It Too
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In this activity, learners build edible models of DNA, while learning basic DNA structure and the rules of base pairing.

Coral Spawning Globe
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This activity models the mass coral spawning event that takes place at Flower Garden Banks National Marine Sanctuary every August.

Generations of Traits
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In this hands-on activity, learners track and record the passage of colored "pompom traits" through three generations of gingerbread people.

Pick the Risk: The Polygenic Pedigree Challenge
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In this activity, learners are challenged to track and record the passage of colored pom poms (representing genes) through generations of a family using a pedigree.

DNA Extraction: Look at your genes!
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Extract your DNA from your very own cells! First, learners swish salt water in their mouth to collect cheek cells and spit the water into a glass.

Handy Family Tree
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In this bilingual (English/Spanish) activity, learners create family trees by tracing the hands of their family members.

Let's Clone a Mouse, Mouse, Mouse...
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Somatic Cell Nuclear Transfer (SCNT) is a cloning method that involves transferring a nucleus from a somatic cell of the individual to be cloned to an enucleated egg.

Gel Electrophoresis
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In this activity, learners simulate the process of DNA fingerprinting by using electricity to separate colored dyes.

DNA Extraction from Wheat Germ
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DNA is the thread of life. Encoded in its genetic sequence is the information that makes each of us unique. This activity allows you to see long, stringy strands of DNA extracted from wheat germ.