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Using Bubbles to Explore Membranes
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In this activity, learners use bubbles to investigate the structure and unique properties of cell membranes. Bubbles serve as macroscopic models that mimic the cells' phospholipid bilayers.

Exploring Size: StretchAbility
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In this game, learners explore the different sizes of things in the world. In this Twister-like game, learners must place a hand or foot on a circle of the right scale - macro, micro, or nano.

Exploring Structures: DNA
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In this activity, learners create a necklace of wheat germ DNA. Learners add alcohol to wheat germ so that the DNA clumps together.

Mushroom Murder Mystery
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In this game (p.28 of PDF), learners discover different fungal lifestyles and the various roles that fungi play in nature. Learners play the roles of fungi and must find their corresponding trees.

Clear Water, Murky Water
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How do scientists measure how clear or murky water in a lake is? How does water clarity (clearness) affect what lives in the lake?

Dirty Oil, Oily Dirt
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In this activity, learners discover how sediment is affected in an oil spill. Learners investigate the differences between heavy and light oil as well as the differences between different sediments.
Soil Secrets
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In this activity (located at the bottom of the page), learners investigate soil and explore the creatures that live in it.

Draw a Monarch Butterfly: Scientific Illustration
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Ivy Rutzky, a scientific assistant at the American Museum of Natural History, introduces an activity where learners create a scientific illustration of a monarch butterfly.
Press Seaweed
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In this activity, learners will collect, dry and press seaweed over the course of four days in a similar way that artists/crafters press flowers.

Bury Me Not!
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This activity (page 2 of the PDF under SciGirls Activity: Bogs) is a full inquiry investigation into decomposition.

Circulatory System Skit: Act out the Flow of Blood
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In this activity, learners act out the flow of blood in the human body! A great way to get learners up and moving while learning about the circulatory system.

Egg Carton Nursery
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In this activity, young learners will make their own flower seed nursery in an egg carton.

Freshwater Ecosystems
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In this activity, learners create a freshwater ecosystem in a large plastic bottle. Learners cut and prepare bottles, then fill with water, aquatic plants, snails and fish.

Screaming String Thing
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In this simple and fun activity, learners discover the relationship between vibration and sound by making a squeaky toy instrument out of simple household materials.

Seeds: Roots and Shoots
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In this indepth hands-on activity, learners build a structure that allows them to observe the growth of roots and the correlation between root growth and stem extension.

Dinosaur Count and Sort
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In this activity, learners sort and count different colored plastic dinosaurs by various attributes including tail length, whether or not the dinosaurs have horns, etc.

Natural Selection Because of Different Color: Camouflage
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In this activity (p.5-6 of PDF), learners investigate natural selection. Learners discover that natural selection, which takes place over decades, can lead to altered populations within a species.

Alike and Different
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This activity (on pages 7-13) has pairs of learners survey an array of similarities and differences between them.
Butterflies in Space
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The Butterflies in Space Teacher's Guide uses "life in space" to encourage learners to conduct their own open-ended scientific investigations.

Rain Forest in Your Room
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This activity (on pages 19-24) introduces learners to the rain forest's layers—emergent, canopy, understory, and forest floor—and has learners make paper lianas (vines that live attached to trees) and