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Lean, Mean Information Machine: Using a Simple Model to Learn about Chromosomal DNA
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Learners observe a model of a cell and its chromosomal DNA made from a plastic egg and dental floss. Use this model to illustrate how much DNA is held in one cell.

Modeling Day and Night
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In this activity (on page 1 of the PDF), learners make a "mini-globe" to investigate the causes of day and night on our planet.

How Do Viruses Recognize a Target Cell?
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This activity demonstrates the specificity of viral vectors for target cells in gene therapy delivery methods using two approaches: 1) STYROFOAM® models demonstrate viral ligand binding to receptor pr

Drain Game
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In this activity (on pages 36-39), learners make a model of a watershed out of paper, then run water down the mountain to simulate how rainfall and pollution affect watersheds.

Have a Heart
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Your heart pumps blood throughout your body in one direction, around in a loop. In this activity, learners will make a model of one type of heart chamber called a ventricle.

Straining Out the Dirt
Learners take on the role of environmental engineers as they design water filters.

Water Clean-up
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This is an activity (located on page 3 of the PDF under Water Clean-up Activity) about the use of reduction agents to decontaminate ground water.

Space Stations: Bones of Contention
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In this activity, learners make models representing bones on Earth and bones that have been in space. They discover what happens to bones without proper exercise and nutrition.

DNA Modeling Activity
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Using pipe cleaners, straws, and beads, learners explore the building blocks of life by creating their own model of DNA.

Space Stations: Sponge Spool Spine
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In this activity, learners simulate what happens to a human spine in space by making Sponge Spool Spines (alternating sponge pieces and spools threaded on a pipe cleaner).

Lung Capacity
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This is an activity about lung capacity. Learners will measure their own lung capacity using a homemade spirometer.

Stream Table
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In this activity, learners use aluminum trays and wooden blocks to form stream tables to investigate river formations in two different landscape scenarios.

Mars from Above: Carving Channels
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In this activity, learners create channel features with flowing water, comparing their observations to real images of Mars and Earth taken by satellites/orbiters.

Biodomes Engineering Design Project
In this design-based activity, learners explore environments, ecosystems, energy flow and organism interactions by creating a model biodome. Learners become engineers who create model ecosystems.

The Watershed Connection
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In this activity, learners interact with a 3-D model of a watershed to better understand the interconnectedness of terrestrial and aquatic environments.

Building a 3-D Space Maze: Escher Staircase
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In this activity (page 95 of the PDF), learners create Escher Staircase models similar to those that were used by Neurolab's Spatial Orientation Team to investigate the processing of information about

Build A Treetop Walkway
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Build and test a scale model of a rainforest canopy walkway.

The Great Plankton Race
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In this activity, learners are challenged to design a planktonic organism that will neither float like a cork nor sink like a stone.
Building a Community From the Ground Up
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In this activity, a group of learners work collaboratively to design and construct a paper model showing the evolution of an environment through multiple stages, from prehistory through the modern cit

Modeling an HIV Particle
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This activity helps learners visualize the Human Immunodeficiency Virus (HIV) by constructing three-dimensional HIV particle models from paper.