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Lean, Mean Information Machine: Using a Simple Model to Learn about Chromosomal DNA
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Learners observe a model of a cell and its chromosomal DNA made from a plastic egg and dental floss. Use this model to illustrate how much DNA is held in one cell.

From Polliwog to Frog
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In this activity, learners discover how frogs' bodies change while growing from a tadpole to a frog. Learners create a simple craft that gives a visual display of the metamorphosis process.

Animal & Plant Cell Slides
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In this activity, learners make slides of onion cells and their own cheek cells. Use this lab to teach learners how to prepare microscope slides and use a microscope.

DNA Modeling Activity
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Using pipe cleaners, straws, and beads, learners explore the building blocks of life by creating their own model of DNA.

Life Size: Line 'em up!
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In this activity on page 1 of the PDF, learners compare the relative sizes of biological objects (like DNA and bacteria) that can't be seen by the naked eye.

Inside DNA
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In this activity (on pages 34-39), learners make a fairly detailed model of DNA using licorice and gumdrops.

Programming Languages: Harold the Robot
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In this activity related to computer programming, learners give directions to a "robot" (either an adult or another learner) and find out which instructions the robot is able to follow, and how their

DNA Nanotechnology
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In this activity, learners explore deoxyribonucleic acid (DNA), a nanoscale structure that occurs in nature.

Close, Closer, Closest
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In this activity, learners perform an experiment that models a chromatography-like process called electrophoresis, a process used to analyze DNA.

Yabba-Dabba You
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In this activity, learners explore genes and traits. Learners investigate their fingerprints and learn how to categorize them.

DNA Extraction from Wheat Germ
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DNA is the thread of life. Encoded in its genetic sequence is the information that makes each of us unique. This activity allows you to see long, stringy strands of DNA extracted from wheat germ.

Evolution in Plane Sight
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In this activity, learners model directed evolution by making paper fly. Learners construct and fly paper airplanes.

DNA Extraction: Look at your genes!
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Extract your DNA from your very own cells! First, learners swish salt water in their mouth to collect cheek cells and spit the water into a glass.

An Inventory of My Traits
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In this genetics meets math activity, learners take inventories of their own easily-observable genetic traits and compare those inventories with other learners in groups.

Chromosome Models: Karyotyping
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This activity was designed for blind learners, but all types of learners can have a tactile opportunity to construct a karyotype, an organized model of an organism’s chromosomes, conveying the chromos

Phylogenetics
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This activity lets learners participate in the process of reconstructing a phylogenetic tree and introduces them to several core bioinformatics concepts, particularly in relation to evolution.

Wear a Chimp on Your Wrist
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Learners construct a bracelet containing two strands of beads, which represents a double strand of DNA that codes for a gene. They match beads to the bases in a section of a chimp's DNA code.

Size Wheel
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In this fun sticker activity, learners will create a size wheel with images of objects of different size, from macroscopic scale (like an ant) to nanoscale (like DNA).

Forensic Science: Hair Sample Investigation
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This activity (on page 2 of the PDF under SciGirls Activity: Forensics) is a full inquiry investigation into how hairs from a crime scene are matched to suspects.

Make Your Own DNA
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Learners match puzzle pieces to outlines of a DNA strand. The puzzle pieces represent the four chemicals making up DNA base pairs: adenine, thymine, guanine, and cytosine.