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Message in a Neuron
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In this activity, learners play a simple card game to learn the sequence of events in the transmission of nervous system signals.

Flashy Fish
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Professor John Endler traveled to Trinidad in the 1970s to study wild guppies. In this activity, learners take part in an online simulation of Endler's work.

Cats and Canaries
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In this math puzzle game, learners work together to use algebraic reasoning and fun clues for solving word puzzles.

Games from Around the World
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This lesson (on pages 46-55 of PDF) features two strategy board games -- one from Ghana and one from China. The first game, Achi, is a cross between checkers and tic-tac-toe.

Color Sudoku
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The popular sudoku puzzles use numbers, but the game could played with any set of 9 different objects!

Reflections
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In this activity, learners play a game and use pattern blocks to explore mirror images and reflection.

Extreme Lifestyles
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In this matching game, learners study the limits of life on Earth to see what other places in the solar system might sustain microbial life.

Number Systems and Number Theory: Factor Game
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In this math lesson, learners play a game to identify the properties of prime, composite, abundant, deficient and perfect numbers.

Wolf Survival is Just a Roll Away
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In this simulation activity, learners will raise a pack of wolves under ten different conditions: without human interference and with human interference.

Memory Match
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In this classic memory game (on pages 37-45 of PDF), learners turn over tiles to reveal images on the back.

Wolf Survival
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In this activity, some learners pretend to be wolves, while the other learners pretend to be the prey of the wolf. The goal of the simulation is to have the wolves work together to survive.

Who Can Harvest a Walleye?
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This activity focuses on interactions within Earth systems and the effects of human activities. In this activity learners build a biomass pyramid.

Help Wanted
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In this interactive board game, learners "hire" different types of scientists to help canine character Ruff Ruffman solve unusual problems.

Exploring Symbiosis
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In this activity, learners discover which plants and animals have symbiotic relationships and how this impacts each organism.

The Adaptation Game
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To convey the concept of how animals adapt to survive, this game asks learners to imagine what adaptations a given animal would need to live in a certain environment—including environments where such