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Learners observe a model of a cell and its chromosomal DNA made from a plastic egg and dental floss. Use this model to illustrate how much DNA is held in one cell.

This marine biology activity (on pages 11-17) introduces learners to kelp (seaweed) forests that grow in the ocean and are home to many species of sea animals.

In this detailed activity (on pages 9-18), learners investigate the body parts of a parasitic ascaris worm by making and dissecting clay models.

In this activity, learners explore how salt water freezes in comparison to fresh water.

Role-playing the parts of chromosomes and centrioles, learners use large chromosome models and nylon cords (spindle fibers and cell membranes) to walk through the processes of mitosis and meiosis.

In this activity on page 3 of the PDF, learners visualize the relative size and structural differences between microbes that have the potential to cause disease.

In this activity, learners simulate nature's water filtration system by devising a system that will filter out both visible and invisible pollutants from water.

In this activity about engineering, nutrition, and physical activity, learners design and build a healthy bone model of a space explorer which is strong enough to withstand increasing amounts of weigh

In this activity, learners simulate the process of DNA fingerprinting by using electricity to separate colored dyes.

In this activity about living things and gravity (page 5 of PDF), learners design and build an exoskeleton or an endoskeleton for an animal of their own invention.

In this activity, learners construct a model of DNA to better understand the structure of DNA and protein synthesis.

In this hands-on activity, learners investigate the functional design of leaves on a tree.

In this activity, learners solidify their conceptualization of cells by building a model of a cell in a ziplock bag.

In this activity, groups of learners work together to create edible models of chemicals involved in autotrophic nutrition.

In this activity (on pages 30-36), learners simulate a dig for ancient pollen, to experience how paleobotanists study fossilized pollen in rocks to learn about early geological and climatological even

This activity helps learners visualize the Human Immunodeficiency Virus (HIV) by constructing three-dimensional HIV particle models from paper.

In this activity, learners use rice grains to model the composition of the atmosphere of the Earth today and in 1880. Learners assemble the model while measuring percentages.

In this activity, learners explore how genetic switches function and the role of genetic switches in the process of evolution.

In this activity, (on page 6 of the PDF under SciGirls Activity: Dinosaurs) learners participate in a hands-on fossil excavation.

In this activity, learners take measurements and create charts to learn about the size of dinosaurs and their relative scale to humans.