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Mystery Box: Making Observations and Collecting Data
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This activity was designed for blind learners, but all types of learners can use it to learn to differentiate between qualitative and quantitative observations and to practice data collection.

Can Nutrients in Water Cause Harm?
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In this water pollution activity, learners create pond water cultures and investigate the effects of adding chemicals or natural nutrients.

Breathing Machine
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In this activity, learners work in teams to construct human lung models from small plastic beverage bottles and balloons.

Mapping the Spread of HIV/AIDS: Trailing the Pandemic
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In this activity, learners act as epidemiologists by mapping the prevalence of HIV/AIDS worldwide.

Lungometer
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In this environmental health activity, learners investigate their own vital lung capacities.

What Does Spit Do?
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Some animals can swallow food whole, but humans have to chew. In this activity, learners will investigate what saliva does chemically to food before we even swallow.

How Sweet It Is
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In this activity (4th activity on the page), learners use their sense of smell to rate and arrange containers filled with different dilutions of a scent (like cologne or fruit juice) in order from wea

Heavy Metal
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In this activity (on pages 25-31 of PDF), learners soak sponges with different amounts of plaster of paris to simulate different levels of calcification in bone formation.

Survival of the Fittest: Variations in the Clam Species Clamys sweetus
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This guided inquiry three-part activity engages learners in thinking about the mechanism of natural selection by encouraging them to formulate questions that can be answered through scientific investi

Reading DNA
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In this activity, learners use edible models of the DNA molecule to transcribe an mRNA sequence, and then translate it into a protein.

DNA and Histone Model
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In this activity, learners construct a 3-D paper model depicting how histone, acetyl and methyl molecules control access to DNA and affect gene DNA expression.

Carbon Cycle Roleplay
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In this creative roleplay activity, learners will explore the various processes of the carbon cycle using movement and props to aid in comprehension.

Make a Comet Model and Eat It!
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In this activity, learners build models of comets, using edible materials, to learn about comets' structure.

Have Your DNA and Eat It Too
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In this activity, learners build edible models of DNA, while learning basic DNA structure and the rules of base pairing.

Survival of the Fittest: Battling Beetles
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This guided inquiry three-part activity engages learners in thinking about the mechanism of natural selection through data collection and pattern recognition.

Rhythm Painting
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In this activity, early learners create paintings by making music and rhythm. Learners place paper in cans, add paint-soaked beans (or pebbles) and put the tops on.

Bendy Bones
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In this activity (on pages 19-24 of PDF), learners soak chicken bones or eggshells in vinegar for several days.
Interference in a Ripple Tank
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In this optics activity, learners explore interference by adding wax blocks to a ripple tank.

Searching for Life
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In this activity, learners discuss how life is defined and conduct a simple experiment, looking for signs of life in three different “soil” samples.

Sensory Hi-Lo Hunt
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In this outdoor activity, learners use only their senses to to find the extremes of several environmental variables or physical factors: wind, temperature, light, slope and moisture.