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Lean, Mean Information Machine: Using a Simple Model to Learn about Chromosomal DNA
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Learners observe a model of a cell and its chromosomal DNA made from a plastic egg and dental floss. Use this model to illustrate how much DNA is held in one cell.

Modeling Day and Night
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In this activity (on page 1 of the PDF), learners make a "mini-globe" to investigate the causes of day and night on our planet.

Identifying Erosion
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In this environmental science activity (page 3 of the PDF), leaners will identify and explain the causes of erosion.

From Polliwog to Frog
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In this activity, learners discover how frogs' bodies change while growing from a tadpole to a frog. Learners create a simple craft that gives a visual display of the metamorphosis process.

How Do Viruses Recognize a Target Cell?
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This activity demonstrates the specificity of viral vectors for target cells in gene therapy delivery methods using two approaches: 1) STYROFOAM® models demonstrate viral ligand binding to receptor pr

String Genome
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In this biology activity (page 5 of the PDF), learners use yarn and sticky labels to build a model of a DNA strand. They discover that DNA is very long, very skinny, and packs well into cells.

Drain Game
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In this activity (on pages 36-39), learners make a model of a watershed out of paper, then run water down the mountain to simulate how rainfall and pollution affect watersheds.

Classification Line-up
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This activity was designed for blind learners, but all types of learners can use it to organize an interactive model for learning the classification system (taxonomy) of living things.

Cells and Walls
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Using toothpicks, straws, or tubes of rolled up newspaper, learners create 3-dimensional models to illustrate the basic structure and function of the cell membrane, and place an object inside to repre

Have a Heart
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Your heart pumps blood throughout your body in one direction, around in a loop. In this activity, learners will make a model of one type of heart chamber called a ventricle.

Straining Out the Dirt
Learners take on the role of environmental engineers as they design water filters.

Water Body Salinities I
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In this activity, learners investigate the different salinity levels of oceans, rivers and estuaries.

Kelp Critters
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This marine biology activity (on pages 11-17) introduces learners to kelp (seaweed) forests that grow in the ocean and are home to many species of sea animals.

Modeling Limits to Cell Size
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This investigation provides learners with a hands-on activity that simulates the changing relationship of surface areas-to-volume for a growing cell.

Water Clean-up
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This is an activity (located on page 3 of the PDF under Water Clean-up Activity) about the use of reduction agents to decontaminate ground water.

A Model Parasite
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In this detailed activity (on pages 9-18), learners investigate the body parts of a parasitic ascaris worm by making and dissecting clay models.

Thinking in Three Dimensions
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In this activity, learners create three-dimensional shapes by making some origami models of simple boxes and containers.

Space Stations: Bones of Contention
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In this activity, learners make models representing bones on Earth and bones that have been in space. They discover what happens to bones without proper exercise and nutrition.

An Apple as Planet Earth
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In this environmental education demonstration (page 6 of the PDF), learners will see a tangible representation of the scarcity of soil resources on earth.

Space Stations: Sponge Spool Spine
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In this activity, learners simulate what happens to a human spine in space by making Sponge Spool Spines (alternating sponge pieces and spools threaded on a pipe cleaner).