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Lean, Mean Information Machine: Using a Simple Model to Learn about Chromosomal DNA
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Learners observe a model of a cell and its chromosomal DNA made from a plastic egg and dental floss. Use this model to illustrate how much DNA is held in one cell.
How Do Viruses Recognize a Target Cell?
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This activity demonstrates the specificity of viral vectors for target cells in gene therapy delivery methods using two approaches: 1) STYROFOAM® models demonstrate viral ligand binding to receptor pr
String Genome
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In this biology activity (page 5 of the PDF), learners use yarn and sticky labels to build a model of a DNA strand. They discover that DNA is very long, very skinny, and packs well into cells.
Cells and Walls
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Using toothpicks, straws, or tubes of rolled up newspaper, learners create 3-dimensional models to illustrate the basic structure and function of the cell membrane, and place an object inside to repre
Modeling Limits to Cell Size
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This investigation provides learners with a hands-on activity that simulates the changing relationship of surface areas-to-volume for a growing cell.
Chromosome Shuffle
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Role-playing the parts of chromosomes and centrioles, learners use large chromosome models and nylon cords (spindle fibers and cell membranes) to walk through the processes of mitosis and meiosis.
Life Size: What's in a microbe?
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In this activity on page 3 of the PDF, learners visualize the relative size and structural differences between microbes that have the potential to cause disease.
The Game of Life: Stem Cell Edition
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In this activity, learners play a game that models what happens as stem cells differentiate into different cell types.
Inside DNA
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In this activity (on pages 34-39), learners make a fairly detailed model of DNA using licorice and gumdrops.
Single-Cell Life
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In this activity, learners create a soil and water model of a single-cell life environment and study living microorganisms.
Visualizing How the Vestibular System Works
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In this activity (page 59 of the PDF), learners spin and observe false eyelashes in jars of water (prepared at least 1 day ahead of time) to investigate the effects of different types of motion on the
Pathways with Friends
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Directed by instructional cards, learners kinesthetically model cell communication by acting as components in a cell signaling pathway.
Traveling Nanoparticles Model
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This is an activity (located on page 3 of the PDF under Nanosilver Activity) about diffusion of small molecules across cell membranes.
The Model Neuron
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In this activity, learners create a model of a neuron by using colored clay or play dough. Learners use diagrams to build the model and then label the parts on a piece of paper.
Make a DNA Model
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In this activity, learners make a 3-D model of DNA using paper and toothpicks. While constructing this model, learners will explore the composition and structure of DNA.
Shake and Make: Charge Recognition
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In this activity (page 10), learners explore how molecules self-assemble according to forces of attraction and repulsion.
Slimy Cells
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In this activity, learners solidify their conceptualization of cells by building a model of a cell in a ziplock bag.
3D-ection: Molecular Shape Recognition
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In this activity (page 12), learners explore how molecules self-assemble and how molecules must fit together, like a lock and key, in order to identify each other and initiate a new function as a comb
Paper Proteins
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In this activity, learners use an origami template to design eight amino acids. Learners configure the amino acids to form a protein. Use this activity to introduce proteins and amino acids.
Viral Packaging
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In this activity, learners create virus models, including nucleic acid and proteins, using simple materials. This resource includes information about virus structure and gene therapy.