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Let's Clone a Mouse, Mouse, Mouse...
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Somatic Cell Nuclear Transfer (SCNT) is a cloning method that involves transferring a nucleus from a somatic cell of the individual to be cloned to an enucleated egg.

lambda DNA Fingerprinting Simulation
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The purpose of this lab activity is to demonstrate (through simulation) how DNA fingerprinting (or DNA profiling) might be used to solve a crime.

Candy Dish Natural Selection
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In this yummy biology activity (page 3 of the PDF), learners participate in a demonstration of natural selection.

Chromosome Shuffle
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Role-playing the parts of chromosomes and centrioles, learners use large chromosome models and nylon cords (spindle fibers and cell membranes) to walk through the processes of mitosis and meiosis.

DNA Detective
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This activity is about collecting and analyzing DNA as part of a criminal investigation.

Gel Electrophoresis
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In this activity, learners simulate the process of DNA fingerprinting by using electricity to separate colored dyes.

Finding a Gene on the Chromosome Map
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In this activity, learners use pedigree and jigsaw puzzles to explore how scientists use genetic information from a family to identify a gene associated with a genetic disorder.

Programming Languages: Harold the Robot
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In this activity related to computer programming, learners give directions to a "robot" (either an adult or another learner) and find out which instructions the robot is able to follow, and how their

Forensic Science: Hair Sample Investigation
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This activity (on page 2 of the PDF under SciGirls Activity: Forensics) is a full inquiry investigation into how hairs from a crime scene are matched to suspects.

Evolutionstechnik or Selection and Variation in the Egyptian Origami Bird (Avis papyrus)
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In order to examine the random nature of mutations and natural selection, learners "breed" clutches of Egyptian Origami Birds (Avis papyrus) using random number generators (dice and coins) to mutate s

Bird Beak Buffet
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In this classic activity, learners investigate natural selection by becoming birds foraging for food on an island.

DNA Fingerprinting
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In this forensics activity, learners solve a mystery using “DNA” taken from the scene of the crime.

Colorful Electrophoresis
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In this activity, learners follow step-by-step instructions to build a gel electrophoresis chamber using inexpensive materials from local hardware and electronic stores.

“Chips” Off the Old Block?
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In this activity, learners bake cookies by following different recipes to better understand genetic mutations. Everyone in the group bakes the same type of cookie: chocolate chip.

Disease Detectives
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In this activity, learners examine antibodies and antibody recognition using a model.

Nano Latch-n-Catch
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In this activity, learners design a therapeutic agent to image and/or cure various diseases in the respiratory system.

Close, Closer, Closest
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In this activity, learners perform an experiment that models a chromatography-like process called electrophoresis, a process used to analyze DNA.

Risk Continuum
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This activity is a whole-group kinesthetic demonstration that shows learners what it means to be in a "risk group" for developing heart disease based on family history and genetics.

Generations of Traits
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In this hands-on activity, learners track and record the passage of colored "pompom traits" through three generations of gingerbread people.

Pick the Risk: The Polygenic Pedigree Challenge
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In this activity, learners are challenged to track and record the passage of colored pom poms (representing genes) through generations of a family using a pedigree.