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Antigen-Antibody Testing: A Visual Simulation or Virtual Reality
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In this biology activity, learners use plastic pipettes to cut wells into the solid gel layer of agar in petri dishes and place solutions of simulated antigen and antibody preparations into the wells.

Piecing It All Together
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Learners create their own piece of history by decorating, shattering, and piecing together a flowerpot "artifact".
Light on Other Planets
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In this math-based activity, learners model the intensity of light at various distances from a light source, and understand how astronomers measure the amount of sunlight that hits our planet and othe

Rubber Blubber Gloves
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In this experiment, learners work in pairs to create two gloves -- one that contains a layer of shortening (blubber) inside, and one that doesn't.

Mapping Sea Level Rise
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In this activity related to climate change, learners create and explore topographical maps as a means of studying sea level rise.

Let's Make a Supernova!
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This fun and simple hands-on astronomy activity lets learners explore what happens when a star explodes.

Forensic Science: Hair Sample Investigation
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This activity (on page 2 of the PDF under SciGirls Activity: Forensics) is a full inquiry investigation into how hairs from a crime scene are matched to suspects.

Shake Table
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This activity guide includes instructions on how to build a "Shake Table" by mounting an eccentric mass (off center) on the shaft of a small dc motor.

Pom Pom Potential
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In this kinesthetic activity, learners move pom-pom "ions" across a membrane to simulate how an action potential is propagated along an axon.

Jumpin' the Gap
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In this simulation of synapses, learners act out communication at the neural level by behaving as pre-synaptic vesicles, neurotransmitters, post-synaptic receptors, secondary messengers and re-uptake

Bark Beetle Infestation Investigation: Estimation and Pheromones
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This activity investigates how bark beetles can threaten forests by having learners estimate the number of infected trees from a photo.

Neural Network Signals
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In this activity, learners create an electrical circuit and investigate how some dissolved substances conduct electricity.

Spill Spread
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In this simulation, learners explore how ocean currents spread all kinds of pollution—including oil spills, sewage, pesticides and factory waste—far beyond where the pollution originates.

Exploring at the Nanoscale
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This lesson focuses on how nanotechnology has impacted our society and how engineers have learned to explore the world at the nanoscale.

Earth Attractions
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In this activity, learners build and test a compass. Learners work in pairs and pretend they are stuck in the wilderness at night.

Why is the Sky Blue?
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In this activity, learners use a flashlight, a glass of water, and some milk to examine why the sky is blue and sunsets are red.

Standing in the Shadow of Earth
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This fun and simple hands-on astronomy activity demonstrates the shadow of the Earth as it rises as a dark blue shadow above the eastern horizon.

Build a Soundscape
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This is a virtual representation of a sound mixer containing pre-looped sounds of animal, insect, and environmental noises.

Magnification vs. Resolution: Can you see the flag on the Moon?
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This fun and simple hands-on astronomy activity lets learners explore the difference between telescope magnification and resolution.

What Causes Pressure?
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In this kinesthetic activity that demonstrates pressure, learners act as air molecules in a "container" as defined by a rope.