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From Polliwog to Frog
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In this activity, learners discover how frogs' bodies change while growing from a tadpole to a frog. Learners create a simple craft that gives a visual display of the metamorphosis process.

Let's Clone a Mouse, Mouse, Mouse...
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Somatic Cell Nuclear Transfer (SCNT) is a cloning method that involves transferring a nucleus from a somatic cell of the individual to be cloned to an enucleated egg.

Close, Closer, Closest
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In this activity, learners perform an experiment that models a chromatography-like process called electrophoresis, a process used to analyze DNA.

Gene Switches
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In this activity, learners explore how genetic switches function and the role of genetic switches in the process of evolution.

The Beaks of the Finches
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In this simulation, learners become birds different beak types. Learners use various tools to represent beaks to pick up seeds and place them in a petri dish.

Bird Beak Buffet
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In this classic activity, learners investigate natural selection by becoming birds foraging for food on an island.

Evolutionstechnik or Selection and Variation in the Egyptian Origami Bird (Avis papyrus)
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In order to examine the random nature of mutations and natural selection, learners "breed" clutches of Egyptian Origami Birds (Avis papyrus) using random number generators (dice and coins) to mutate s

Glow Up
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In this activity, learners explore chemiluminescence and fluorescence. Learners examine 3 different solutions in regular light, in the dark with added bleach solution, and under a black light.

Biotechnology Through Time
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In this activity, learners investigate the history and development of agricultural biotechnology.

Living Clocks
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In this activity about daily rhythms (on page 17 of the PDF), learners will explore circadian patterns in humans, animals and plants.

Life Story
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In this two-part activity, learners compare and contrast a variety of life cycles to better understand different organisms and how they develop.

Coral Spawning Globe
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This activity models the mass coral spawning event that takes place at Flower Garden Banks National Marine Sanctuary every August.

A Recipe for Traits
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In this genetics activity, learners create and decode a “DNA recipe” for a dog by randomly selecting strips of paper that represent DNA.

Using a Sundial
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In this activity (on page 12 of the PDF), learners make a sundial (shadow clock) appropriate for their geographic location in the northern hemisphere and use it to tell time.

Evolution in Action: Isolation and Speciation in the Lower Congo River
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In this guided discussion activity, learners watch a video about Central Africa's Lower Congo River, one of the most biologically diverse rivers in the world.

Sequence Bracelets
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In this craft-based activity, learners make DNA sequence bracelets that carry the code of an organism such as a human, trout, chimpanzee or butterfly.

Keeping a Field Journal
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In this activity, learners start their own field journal to better understand the wildlife in their area.

Mapping Mockingbirds
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This lesson plan revolves around studying the speciation of the Galápagos mockingbirds, which are on display at the California Academy of Sciences.

Giant Chromosomes: Fruit Fly DNA and You
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Many of the genetic sequences found in the fruit fly genome are similar to those found in humans.

Transformation of E. coli Using Green Fluorescent Protein
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In this activity related to plant biotechnology, learners transform a strain of E. coli using green fluorescent protein from a bioluminescent jellies.