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Lean, Mean Information Machine: Using a Simple Model to Learn about Chromosomal DNA
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Learners observe a model of a cell and its chromosomal DNA made from a plastic egg and dental floss. Use this model to illustrate how much DNA is held in one cell.

Supporting Structures
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In this activity about living things and gravity (page 5 of PDF), learners design and build an exoskeleton or an endoskeleton for an animal of their own invention.

Modeling an HIV Particle
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This activity helps learners visualize the Human Immunodeficiency Virus (HIV) by constructing three-dimensional HIV particle models from paper.

Earth Atmosphere Composition
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In this activity, learners use rice grains to model the composition of the atmosphere of the Earth today and in 1880. Learners assemble the model while measuring percentages.

Gene Switches
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In this activity, learners explore how genetic switches function and the role of genetic switches in the process of evolution.

Size, Scale and Models
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In this activity, learners take measurements and create charts to learn about the size of dinosaurs and their relative scale to humans.

Waterhouse Hawkins and the Nano Dinosphere Museum
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In this activity, learners explore dinosaurs and fossils by creating a diorama.

I Spy, Describing Insects
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In this activity, learners observe and describe the physical and behavioral characteristics of insects, including crickets.

Tidepool in the Classroom
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In this activity (page 4 of the pdf), learners build a model of a tide pool, using chicken wire, paper mache, and other craft materials.

Control a Bird’s Flight
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In this engineering design challenge, learners make a bird and then control its flight with attached strings.

Exploring an Ecosystem
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In this ecology activity, learners make a model water-based ecosystem called a terraqua column. The column (in a large soda bottle) includes pond water, duckweed, sand or gravel, and small snails.

DNA Jewelry Models
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In this activity, learners construct a model of DNA to better understand the structure of DNA and protein synthesis.

Slimy Cells
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In this activity, learners solidify their conceptualization of cells by building a model of a cell in a ziplock bag.

Candy Chemosynthesis
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In this activity, groups of learners work together to create edible models of chemicals involved in autotrophic nutrition.

Create a Coral Reef
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Educator Amy O'Donnell from the American Museum of Natural History guides learners to create a diorama of a coral reef.
Leaves: Designing Leaf Arrangements on a Branch
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In this hands-on activity, learners investigate the functional design of leaves on a tree.

Life Size: What's in a microbe?
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In this activity on page 3 of the PDF, learners visualize the relative size and structural differences between microbes that have the potential to cause disease.

Born of Blood: Craft Stick Chromosomes
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In this activity, learners work in groups to match craft sticks that represent chromosomes. Learners must define critical attributes of their chromosomes as they look for matching chromosomes.

Clean Water: Is It Drinkable?
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In this activity, learners simulate nature's water filtration system by devising a system that will filter out both visible and invisible pollutants from water.

Gel Electrophoresis
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In this activity, learners simulate the process of DNA fingerprinting by using electricity to separate colored dyes.