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From Polliwog to Frog
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In this activity, learners discover how frogs' bodies change while growing from a tadpole to a frog. Learners create a simple craft that gives a visual display of the metamorphosis process.

How Do Viruses Recognize a Target Cell?
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This activity demonstrates the specificity of viral vectors for target cells in gene therapy delivery methods using two approaches: 1) STYROFOAM® models demonstrate viral ligand binding to receptor pr

Drain Game
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In this activity (on pages 36-39), learners make a model of a watershed out of paper, then run water down the mountain to simulate how rainfall and pollution affect watersheds.

DNA Modeling Activity
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Using pipe cleaners, straws, and beads, learners explore the building blocks of life by creating their own model of DNA.

Space Stations: Sponge Spool Spine
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In this activity, learners simulate what happens to a human spine in space by making Sponge Spool Spines (alternating sponge pieces and spools threaded on a pipe cleaner).

Lung Capacity
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This is an activity about lung capacity. Learners will measure their own lung capacity using a homemade spirometer.

Mars from Above: Carving Channels
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In this activity, learners create channel features with flowing water, comparing their observations to real images of Mars and Earth taken by satellites/orbiters.

Dinosaur Homes
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In this activity about dinosaurs and survival, learners use scrap materials to create a miniature dinosaur habitat that includes a food source, water source, and shelter.

How We Know What The Dinosaurs Looked Like: How Fossils Were Formed
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In this activity (p.7-8 of PDF), learners examine fossil formation.

Build A Treetop Walkway
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Build and test a scale model of a rainforest canopy walkway.

Mars from Above: Viewing Volcanoes
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In this activity, learners create volcanoes like those they have examined on Earth and Mars through images taken by spacecraft.

Chromosome Models: Karyotyping
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This activity was designed for blind learners, but all types of learners can have a tactile opportunity to construct a karyotype, an organized model of an organism’s chromosomes, conveying the chromos

Making Vocal Cords
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In this activity, learners imitate the way vocal cords work by building a model from a plastic cup, rubber band, and a straw.

Lub Dub: Make a Heart Valve
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Learners will construct a model of a heart valve using a film canister, a piece of masking tape, and a piece of paper.

Clean Me Up, Snotty
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Learners will explore the chemistry of mucous and its importance to our health by following a process to make their own replica "snot." The activity includes a time and age recommendation, a materials

Origami DNA
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In this activity, learners create an origami model of DNA, demonstrating its double helix structure.

Coral Polyp
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In this activity, learners will create their own coral polyps - the basis for a coral reef.

Wetland Filter Model
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In this quick activity (located on page 2 of the PDF under GPS Wetlands Activity), learners will model how wetlands act as natural filters for the environment.

Moving Model Glacier
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In this goopy activity (page 2 of PDF under GPS: Glaciers Activity), learners will model glacial movement with “gak,” a white glue and liquid starch mixture.

The Model Neuron
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In this activity, learners create a model of a neuron by using colored clay or play dough. Learners use diagrams to build the model and then label the parts on a piece of paper.