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Learners observe a model of a cell and its chromosomal DNA made from a plastic egg and dental floss. Use this model to illustrate how much DNA is held in one cell.

Role-playing the parts of chromosomes and centrioles, learners use large chromosome models and nylon cords (spindle fibers and cell membranes) to walk through the processes of mitosis and meiosis.

In this activity on page 3 of the PDF, learners visualize the relative size and structural differences between microbes that have the potential to cause disease.

In this activity, learners simulate nature's water filtration system by devising a system that will filter out both visible and invisible pollutants from water.

In this activity about engineering, nutrition, and physical activity, learners design and build a healthy bone model of a space explorer which is strong enough to withstand increasing amounts of weigh

In this activity, learners simulate the process of DNA fingerprinting by using electricity to separate colored dyes.

In this activity about living things and gravity (page 5 of PDF), learners design and build an exoskeleton or an endoskeleton for an animal of their own invention.

In this activity, learners construct a model of DNA to better understand the structure of DNA and protein synthesis.

In this hands-on activity, learners investigate the functional design of leaves on a tree.

In this activity, learners solidify their conceptualization of cells by building a model of a cell in a ziplock bag.

In this activity, groups of learners work together to create edible models of chemicals involved in autotrophic nutrition.

This activity helps learners visualize the Human Immunodeficiency Virus (HIV) by constructing three-dimensional HIV particle models from paper.

In this activity, learners explore how genetic switches function and the role of genetic switches in the process of evolution.

In this activity, (on page 6 of the PDF under SciGirls Activity: Dinosaurs) learners participate in a hands-on fossil excavation.

In this activity, learners take measurements and create charts to learn about the size of dinosaurs and their relative scale to humans.

In this ecology activity, learners make a model water-based ecosystem called a terraqua column. The column (in a large soda bottle) includes pond water, duckweed, sand or gravel, and small snails.

In this activity, learners explore dinosaurs and fossils by creating a diorama.

In this activity (page 4 of the pdf), learners build a model of a tide pool, using chicken wire, paper mache, and other craft materials.

This activity (located on page 4 of the PDF under GPS: Baby Dinosaurs Activity) is a full inquiry investigation to determine the age of fossils based on where they are discovered.

In this genetics activity, learners create imaginary creatures known as "Reebops" to explore the relationships between genes and inherited traits.