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Modeling Day and Night
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In this activity (on page 1 of the PDF), learners make a "mini-globe" to investigate the causes of day and night on our planet.

Drain Game
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In this activity (on pages 36-39), learners make a model of a watershed out of paper, then run water down the mountain to simulate how rainfall and pollution affect watersheds.
Mercury in the Environment
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In this environmental science lesson, learners will examine the dangers of mercury and how humans contribute to growing mercury emissions on Earth.

Disease Detective
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This activity (on pages 35-43) lets learners analyze a "herd of elk" to detect the spread of a bacterial disease called brucellosis.

Let's Clone a Mouse, Mouse, Mouse...
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Somatic Cell Nuclear Transfer (SCNT) is a cloning method that involves transferring a nucleus from a somatic cell of the individual to be cloned to an enucleated egg.

lambda DNA Fingerprinting Simulation
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The purpose of this lab activity is to demonstrate (through simulation) how DNA fingerprinting (or DNA profiling) might be used to solve a crime.

Water Clean-up
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This is an activity (located on page 3 of the PDF under Water Clean-up Activity) about the use of reduction agents to decontaminate ground water.

Water Body Salinities II
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In this activity, learners discuss the different salinities of oceans, rivers and estuaries.

Toxic Popcorn Design Challenge
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In this activity, learners explore the engineering design process (EDP)—the process engineers use to solve design challenges.

The Carbon Cycle and its Role in Climate Change: Activity 3
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In this activity, learners explore the human influences on the carbon cycle and examine how fossil fuels release carbon.

Amazon Water Cycle Roleplay
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In this creative roleplay activity, learners will explore the various processes of the water cycle using movement, sound, and props to aid in comprehension.

Finding a Gene on the Chromosome Map
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In this activity, learners use pedigree and jigsaw puzzles to explore how scientists use genetic information from a family to identify a gene associated with a genetic disorder.
Coincidental Colonization
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In this game of chance, learners will discover how organisms colonized the Galápagos Islands, experiencing how chance plays a role in the successful dispersal of species to new areas.

In the Toilet
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This activity explores the basic workings of a siphon, which is the core technology that makes toilets work.
The Earth's Timeline
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In this group activity, learners will mark important developments of life on Earth on a timeline (each foot in length representing 200 million years).
Light on Other Planets
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In this math-based activity, learners model the intensity of light at various distances from a light source, and understand how astronomers measure the amount of sunlight that hits our planet and othe

Future Moon: The Footsteps of Explorers
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In this activity, learners drop impactors onto layers of graham crackers!

Forensic Science: Hair Sample Investigation
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This activity (on page 2 of the PDF under SciGirls Activity: Forensics) is a full inquiry investigation into how hairs from a crime scene are matched to suspects.

Evolutionstechnik or Selection and Variation in the Egyptian Origami Bird (Avis papyrus)
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In order to examine the random nature of mutations and natural selection, learners "breed" clutches of Egyptian Origami Birds (Avis papyrus) using random number generators (dice and coins) to mutate s

Dinosaur Dig
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This is an activity about dinosaurs, fossils, and the work of paleontologists. Learners use hand tools (paint brushes, scoops, and sifters) to unearth fossil specimens in tubs of birdseed.