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What Molecules Make the Holes in Bread?
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In this activity, learners will discover why there are holes in bread.

Water Quality and pH Levels in Aquatic Ecosystems
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In this fun and in depth hands-on experiment, learners test various liquid samples (distilled water, lemon juice, vinegar, and baking soda mixed with water) to determine their pH levels and identify e

Natural Indicators
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Learners combine different plant solutions -- made from fruits, vegetables, and flowers -- with equal amounts of vinegar (acid), water (neutral), and ammonia (base).

Density Rainbow and the Great Viscosity Race
Learners conduct two activities to investigate two properties of liquids: density and viscosity. In a clear container, learners stack 7 different liquids which will layer according to their density.

Corals and Chemistry
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In this activity, learners investigate how increased carbon dioxide (CO2) emissions from the burning of fossil fuels is changing the acidity (pH) of the ocean and affecting coral reefs and other marin

Glow Up
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In this activity, learners explore chemiluminescence and fluorescence. Learners examine 3 different solutions in regular light, in the dark with added bleach solution, and under a black light.

Build a Rocket - and a Launch Pad!
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In this activity, learners construct a rocket powered by the pressure generated from an effervescing antacid tablet reacting with water, and build a launch pad for their rocket.

Air, It's Really There
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This lesson focuses on molecular motion in gases. Learners compare the mass of a basketball when it is deflated and after it has been inflated.

Disappearing Statues
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In this activity (on page 8), learners model how marble statues and buildings are affected by acid rain.

Mixtures and Solutions
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This activity was designed for blind learners, but all types of learners can use it to investigate heterogeneous and homogeneous mixtures and solutions, identify the differences, and explore the conce

Rocket Science
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Learners create a small explosion by collecting hydrogen and oxygen gas together and squeezing them into a flame.

Sniffing for a Billionth
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This is an activity (located on page 4 of the PDF under What's Nano? Activity) about size and scale.

Pickle-oh!: Musical Pickle Instrument
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What's a Pickle-Oh? Two pieces of pickle on a stick are connected to a Pico Cricket (micro controller). When you slide the pickles apart the note changes.

Biobarcodes: Antibodies and Nanosensors
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In this activity/demo, learners investigate biobarcodes, a nanomedical technology that allows for massively parallel testing that can assist with disease diagnosis.

Pom Pom Potential
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In this kinesthetic activity, learners move pom-pom "ions" across a membrane to simulate how an action potential is propagated along an axon.

Aerogel
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This activity/demo introduces learners to aerogel, a glass nanofoam. Learners discover how aerogel is made and how well it insulates as well as learn about aerogel's other unique properties.

Self-Portrait Silhouettes: Activity 2
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In this activity, learners make a photographic image—without a camera!

Flower Power
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In this activity, learners will experiment with changing flower colors. Learners will investigate the effects of acids and bases on flower colors.

Jumpin' the Gap
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In this simulation of synapses, learners act out communication at the neural level by behaving as pre-synaptic vesicles, neurotransmitters, post-synaptic receptors, secondary messengers and re-uptake

Neutralizing Acids and Bases
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Learners use their knowledge of color changes with red cabbage indicator to neutralize an acidic solution with a base and then neutralize a basic solution with an acid.