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Lean, Mean Information Machine: Using a Simple Model to Learn about Chromosomal DNA
Source Institutions
Learners observe a model of a cell and its chromosomal DNA made from a plastic egg and dental floss. Use this model to illustrate how much DNA is held in one cell.
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Animal & Plant Cell Slides
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In this activity, learners make slides of onion cells and their own cheek cells. Use this lab to teach learners how to prepare microscope slides and use a microscope.
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DNA Detective
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This activity is about collecting and analyzing DNA as part of a criminal investigation.
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Does Sunscreen Protect My DNA?
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In this laboratory experiment, learners explore how effectively different sunscreens protect yeast cells from damage caused by ultraviolet (UV) radiation.
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Inside DNA
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In this activity (on pages 34-39), learners make a fairly detailed model of DNA using licorice and gumdrops.
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Forensic Science: Hair Sample Investigation
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This activity (on page 2 of the PDF under SciGirls Activity: Forensics) is a full inquiry investigation into how hairs from a crime scene are matched to suspects.
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Glow Up
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In this activity, learners explore chemiluminescence and fluorescence. Learners examine 3 different solutions in regular light, in the dark with added bleach solution, and under a black light.
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Make a DNA Model
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In this activity, learners make a 3-D model of DNA using paper and toothpicks. While constructing this model, learners will explore the composition and structure of DNA.
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Nano Latch-n-Catch
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In this activity, learners design a therapeutic agent to image and/or cure various diseases in the respiratory system.
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Make Your Own DNA
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Learners match puzzle pieces to outlines of a DNA strand. The puzzle pieces represent the four chemicals making up DNA base pairs: adenine, thymine, guanine, and cytosine.
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DNA Extraction: Look at your genes!
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Extract your DNA from your very own cells! First, learners swish salt water in their mouth to collect cheek cells and spit the water into a glass.
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Life Size: Line 'em up!
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In this activity on page 1 of the PDF, learners compare the relative sizes of biological objects (like DNA and bacteria) that can't be seen by the naked eye.
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Close, Closer, Closest
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In this activity, learners perform an experiment that models a chromatography-like process called electrophoresis, a process used to analyze DNA.
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Have Your DNA and Eat It Too
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In this activity, learners build edible models of DNA, while learning basic DNA structure and the rules of base pairing.
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Chromosome Models: Karyotyping
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This activity was designed for blind learners, but all types of learners can have a tactile opportunity to construct a karyotype, an organized model of an organism’s chromosomes, conveying the chromos
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What Sort?
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In this activity (on pages 22-33), learners do the kind of work genetic scientists do, sorting and comparing (images of) genetic material strands called chromosomes.
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Size Wheel
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In this fun sticker activity, learners will create a size wheel with images of objects of different size, from macroscopic scale (like an ant) to nanoscale (like DNA).
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Exploring Structures: DNA
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In this activity, learners create a necklace of wheat germ DNA. Learners add alcohol to wheat germ so that the DNA clumps together.
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Coral Spawning Globe
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This activity models the mass coral spawning event that takes place at Flower Garden Banks National Marine Sanctuary every August.
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Self-Assembly Game
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This is a quick game about self-assembly (page 2 of PDF under Self-Assembly Activity). Like the molecules of DNA, learners will self-assemble into a pattern by following a simple set of rules.