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Abuse-a-Cyst
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In this activity, learners examine how brine shrimp populations can survive in some of the harshest environments.

Water Body Salinities I
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In this activity, learners investigate the different salinity levels of oceans, rivers and estuaries.

lambda DNA Fingerprinting Simulation
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The purpose of this lab activity is to demonstrate (through simulation) how DNA fingerprinting (or DNA profiling) might be used to solve a crime.

Testing for Life's Molecules
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In this activity, learners conduct tests for proteins, glucose, and starch.

Mars from Above: Carving Channels
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In this activity, learners create channel features with flowing water, comparing their observations to real images of Mars and Earth taken by satellites/orbiters.

Crayfish Investigations
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This activity has learners interacting with live crayfish, but could be adapted for a variety of similar hardy and interesting organisms.

What's In Your Breath?
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In this activity, learners test to see if carbon dioxide is present in the air we breathe in and out by using a detector made from red cabbage.

The Watershed Connection
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In this activity, learners interact with a 3-D model of a watershed to better understand the interconnectedness of terrestrial and aquatic environments.

Clap Sensor: Build a Sound Sensor Using a Pico Cricket
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This activity requires a Pico Cricket (tiny computer). Learners work on designing and building a sound sensor out of household materials, like plastic wrap and cardboard.
What Does Life Need to Live?
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In this astrobiology activity (on page 11 of the PDF), learners consider what organisms need in order to live (water, nutrients, and energy).

Forensic Science: Hair Sample Investigation
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This activity (on page 2 of the PDF under SciGirls Activity: Forensics) is a full inquiry investigation into how hairs from a crime scene are matched to suspects.

Low-Tech Water Filter for High-Impact Clean
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In this activity, learners consider the water features they might enjoy at a community park--a pond, brook, water playground (or "sprayground"), or pool--and what happens to the water over time.

Make a Cast of a Tyrannosaurus rex Fossil
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In this activity, learners explore dinosaur fossils by making cast models of a T. rex. First, learners read about and research how dinosaur fossils form.

Runaway Runoff
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When it rains, water can collect on top of and seep into the ground. Water can also run downhill, carrying soil and pollution with it.

Moving and Working in Space
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In this activity, groups of four learners must complete a set of four manual tasks. The restrictions are that they must complete the tasks in a limited time while wearing garden or rubber gloves.

Oil Spill Solutions
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In this activity, learners explore how environmental engineers might approach solving the problem of an oil spill.

Nano Latch-n-Catch
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In this activity, learners design a therapeutic agent to image and/or cure various diseases in the respiratory system.

Disease Detectives
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In this activity, learners examine antibodies and antibody recognition using a model.

Slimy Cells
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In this activity, learners solidify their conceptualization of cells by building a model of a cell in a ziplock bag.

Anti-Gravity Mirror
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In this demonstration, amaze learners by performing simple tricks using mirrors. These tricks take advantage of how a mirror can reflect your right side so it appears to be your left side.