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Abuse-a-Cyst
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In this activity, learners examine how brine shrimp populations can survive in some of the harshest environments.

Water Body Salinities I
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In this activity, learners investigate the different salinity levels of oceans, rivers and estuaries.

lambda DNA Fingerprinting Simulation
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The purpose of this lab activity is to demonstrate (through simulation) how DNA fingerprinting (or DNA profiling) might be used to solve a crime.

Hot Spot
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In this activity, learners explore the invisible infrared radiation from an electric heater.

Look Into Infinity
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Learners use two mirrors to explore how images of images of images can repeat forever.

Stereoscope
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In this activity, learners construct a device that allows them to view 2-D images in 3-D.

What's In Your Breath?
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In this activity, learners test to see if carbon dioxide is present in the air we breathe in and out by using a detector made from red cabbage.

Testing for Life's Molecules
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In this activity, learners conduct tests for proteins, glucose, and starch.

Forensic Science: Hair Sample Investigation
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This activity (on page 2 of the PDF under SciGirls Activity: Forensics) is a full inquiry investigation into how hairs from a crime scene are matched to suspects.

Clap Sensor: Build a Sound Sensor Using a Pico Cricket
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This activity requires a Pico Cricket (tiny computer). Learners work on designing and building a sound sensor out of household materials, like plastic wrap and cardboard.

Crayfish Investigations
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This activity has learners interacting with live crayfish, but could be adapted for a variety of similar hardy and interesting organisms.

Glass and Mirrors: An Inside Look at Telescopes
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This hands-on astronomy activity allows you to create a “cutaway” telescope to clearly show how reflector and refractor telescopes work.

Biological Succession in a Microecosystem
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This laboratory activity helps learners understand the concept of biological succession by simulating the process in a microenvironment with various protozoans.

Science Cooks!
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In this health, cooking, and math activity, learners explore nutrition and examine nutrition labels.

Disease Detectives
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In this activity, learners examine antibodies and antibody recognition using a model.

Slimy Cells
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In this activity, learners solidify their conceptualization of cells by building a model of a cell in a ziplock bag.

Anti-Gravity Mirror
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In this demonstration, amaze learners by performing simple tricks using mirrors. These tricks take advantage of how a mirror can reflect your right side so it appears to be your left side.

Nano Latch-n-Catch
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In this activity, learners design a therapeutic agent to image and/or cure various diseases in the respiratory system.

Oil Spill Solutions
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In this activity, learners explore how environmental engineers might approach solving the problem of an oil spill.
What Does Life Need to Live?
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In this astrobiology activity (on page 11 of the PDF), learners consider what organisms need in order to live (water, nutrients, and energy).