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Lean, Mean Information Machine: Using a Simple Model to Learn about Chromosomal DNA
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Learners observe a model of a cell and its chromosomal DNA made from a plastic egg and dental floss. Use this model to illustrate how much DNA is held in one cell.

How Do Viruses Recognize a Target Cell?
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This activity demonstrates the specificity of viral vectors for target cells in gene therapy delivery methods using two approaches: 1) STYROFOAM® models demonstrate viral ligand binding to receptor pr

Modeling Limits to Cell Size
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This investigation provides learners with a hands-on activity that simulates the changing relationship of surface areas-to-volume for a growing cell.

Life Size: What's in a microbe?
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In this activity on page 3 of the PDF, learners visualize the relative size and structural differences between microbes that have the potential to cause disease.

Single-Cell Life
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In this activity, learners create a soil and water model of a single-cell life environment and study living microorganisms.

Traveling Nanoparticles Model
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This is an activity (located on page 3 of the PDF under Nanosilver Activity) about diffusion of small molecules across cell membranes.

The Model Neuron
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In this activity, learners create a model of a neuron by using colored clay or play dough. Learners use diagrams to build the model and then label the parts on a piece of paper.

Macro-Microarray
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In this activity, learners explore the "nuts and bolts" of gene chips.

Make a DNA Model
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In this activity, learners make a 3-D model of DNA using paper and toothpicks. While constructing this model, learners will explore the composition and structure of DNA.

Slimy Cells
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In this activity, learners solidify their conceptualization of cells by building a model of a cell in a ziplock bag.

Candy Chemosynthesis
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In this activity, groups of learners work together to create edible models of chemicals involved in autotrophic nutrition.

Viral Packaging
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In this activity, learners create virus models, including nucleic acid and proteins, using simple materials. This resource includes information about virus structure and gene therapy.

Modeling an HIV Particle
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This activity helps learners visualize the Human Immunodeficiency Virus (HIV) by constructing three-dimensional HIV particle models from paper.

What Is a Neuron?
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This neuroscience activity introduces learners to how messages are sent and received by neurons. Learners use modeling clay and pipe cleaners to build model neurons.

Reading DNA
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In this activity, learners use edible models of the DNA molecule to transcribe an mRNA sequence, and then translate it into a protein.

DNA and Histone Model
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In this activity, learners construct a 3-D paper model depicting how histone, acetyl and methyl molecules control access to DNA and affect gene DNA expression.

Have Your DNA and Eat It Too
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In this activity, learners build edible models of DNA, while learning basic DNA structure and the rules of base pairing.

Chromosome Models: Karyotyping
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This activity was designed for blind learners, but all types of learners can have a tactile opportunity to construct a karyotype, an organized model of an organism’s chromosomes, conveying the chromos

Building a 3-D Space Maze: Escher Staircase
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In this activity (page 95 of the PDF), learners create Escher Staircase models similar to those that were used by Neurolab's Spatial Orientation Team to investigate the processing of information about

Human Impact on Estuaries: A Terrible Spill in Grand Bay
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In this activity, learners make a model of a pollution spill that occurred at Bangs Lake in Mississippi and measure water quality parameters in their model.