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Cutting it Down to Nano
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This simple activity uses paper and scissors to convey two key concepts to learners: the nanoscale is very small and working on the nanoscale requires special tools.

How to Make a Spore Print
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In this activity (p.25 of PDF), learners investigate spores. Mushrooms produce millions of spores which are equivalent to the seeds of plants but without the massive food reserves.

Coffee to Carbon
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In this activity, learners place cards featuring biological structures in order by their relative size from largest to smallest.

Exploring Tools: Mitten Challenge
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In this activity, learners build a LEGO® structure while wearing mittens. This activity shows learners how difficult it is to build small things when your tools are too big.

Perspectives: Powers of 10
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In this activity, learners complete a series of drawing activities to explore scale and powers of 10. Learners first trace each other on 1-meter-square pieces of paper.
Polarized Light
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In this optics activity, learners experiment with polarizers (small dark rectangles) to examine light intensity.

Exploring the Nanoworld with LEGO Bricks: Probing the Structure of Materials at the Nanoscale
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In this activity (pages 17-31), learners are introduced to techniques that are used to determine the structures of solid materials.

Paper Cutting
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In this activity about scale, learners investigate the world of the very small by cutting a 28 centimeter strip of paper in half as many times as they can.

Modeling Limits to Cell Size
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This investigation provides learners with a hands-on activity that simulates the changing relationship of surface areas-to-volume for a growing cell.

Giant Chromosomes: Fruit Fly DNA and You
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Many of the genetic sequences found in the fruit fly genome are similar to those found in humans.

Diatom Ooze: Ooze Clues
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In this activity, learners will plot the distribution of various oozes using information from sediment maps.

Free-living and Plant-Parasitic Nematodes (Roundworms)
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This lesson introduces learners to the world of nematodes (roundworms).

What Cells Can I See in Muscle and Spinal Cord Tissues?
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In this activity (page 37 of the PDF), learners observe, on a prepared slide, muscle and spinal cord cells from a rat.

Tabletop Biosphere
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In this activity, learners create a sealed, mini ecosystem that supplies freshwater shrimp with food, oxygen, and waste processing for at least three months.

Magnifying and Observing Cells
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In this activity related to microbes, learners make slides of cells from an onion skin and Elodea (American or Canadian waterweed) to observe under a microscope.

Comparing Sizes of Microorganisms
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In this activity related to microbes, learners create scale models of microorganisms and compare relative sizes of common bacteria, viruses, fungi and protozoa using metric measures: meters, centimete

Size and Scale: Probing and Predicting
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In this quick activity about predicting (located on page 2 of the PDF under Where's Nano?

Plant Parts and Their Diseases
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This exercise is designed to teach young learners the different parts of a plant (root, stems, leaves, flowers, fruit, and seeds), the basic functions of each part, and to show that tiny microscopic o

DNA the Easy Way
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This demonstration can be used to help learners visualize DNA by lysing (breaking open) bacterial cells on a slide and “stringing up” the DNA with a toothpick in less than one minute.

Forces at the Nanoscale: Nano Properties of Everyday Plants
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This is an activity (located on page 3 of PDF under Nasturtium Leaves Activity) about surface tension.