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Building a 3-D Space Maze: Escher Staircase
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In this activity (page 95 of the PDF), learners create Escher Staircase models similar to those that were used by Neurolab's Spatial Orientation Team to investigate the processing of information about

Spill Spread
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In this simulation, learners explore how ocean currents spread all kinds of pollution—including oil spills, sewage, pesticides and factory waste—far beyond where the pollution originates.

Experimenting with Naked Eggs
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In this activity about osmosis, learners use a naked egg (one with a dissolved eggshell) to learn about selectively permeable membranes.

Supporting Structures
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In this activity about living things and gravity (page 5 of PDF), learners design and build an exoskeleton or an endoskeleton for an animal of their own invention.

Weighty Questions
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In this activity about humans and space travel (page 1 of PDF), learners compare and contrast the behavior of a water-filled plastic bag, both outside and inside of a container of water.

A Merry-Go-Round for Dirty Air
Learners build a model of a pollution control device--a cyclone. A cyclone works by whirling the polluted air in a circle and accumulating particles on the edges of the container.

A Book About Me
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In this math activity, each learner creates a book about themselves using a template. Learners discuss the different parts of the body and practice measuring their body parts using crayons.

Extreme Lifestyles
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In this matching game, learners study the limits of life on Earth to see what other places in the solar system might sustain microbial life.

Destination Tidepool
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In this activity (page 7 of pdf), learners research tide pool ecosystems, and then create brochures that "advertise" these environments.

Under Pressure: Your Blood Pressure
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During this lesson, learners will determine their blood pressure and learn about systolic and diastolic pressures.

Target Recognition and Synapse Formation During Development
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In this activity about neuron/target muscle recognition (page 44 of the PDF), learners arranged in two rows facing away from each other use string to simulate neural development.

Pathways with Friends
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Directed by instructional cards, learners kinesthetically model cell communication by acting as components in a cell signaling pathway.

Penny Rubbing
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In this art-related activity, learners make a coin rubbing—a process similar to what archeologists may do with ancient artifacts. This activity can be used in connection with a history or art lesson.

DNA Extraction: Look at your genes!
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Extract your DNA from your very own cells! First, learners swish salt water in their mouth to collect cheek cells and spit the water into a glass.

Our Sense of Sight: How We Perceive Movement, Depth and Illusions
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In this activity, learners investigate visual perception as well as plan and conduct their own experiments.

Traveling Tapeworm
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In this "gross" activity (on pages 34-46), learners make a life-size model of a human digestive tract, and follow the life of a beef tapeworm as it makes its way through.

An Inventory of My Traits
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In this genetics meets math activity, learners take inventories of their own easily-observable genetic traits and compare those inventories with other learners in groups.
Hazardous Chemicals in Your Neighborhood
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In this environmental science lesson, learners will examine hazardous chemicals and their effects on human health and the environment.

Smaller Than You Think
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Learners compare a life-size drawing of a Tyrannosaurus rex head and a full-size Sinornithosaurus body to understand that dinosaurs varied in size.

Stepping Out: Hop, Skip, Jump
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In this activity, learners explore and experiment how we can use our bodies everyday to get from one place to another.